L-Valine-1-13C
Based on 1 Customer Validation
L-Valine-1-13C ((S)-Valine-1-13C) is the 13C-labeled L-Valine (HY-N0717). L-Valine ((S)-Valine) is a nonlinear semiorganic material. L-Valine causes lipid peroxidation and accumulation of malondialdehyde (MDA), exhibits inhibitory activity against cyanobacteria. L-Valine inhibits multidrug-resistant bacteria through activation of PI3K/Akt signaling pathway and inhibition of arginase.
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- Pureté : 99.75%
- CAS No.: 81201-85-6
- Formule: C413CH11NO2
- Masse moléculaire:118.14
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Stockage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 81201-85-6
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Unlabeled CAS 72-18-4
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Appearance Solid
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Masse moléculaire 118.14
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Formule C413CH11NO2
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Color White to off-white
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SMILES
N[C@@H](C(C)C)[13C](O)=O
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Synonyms
(S)-Valine-1-13C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
In Vitro:
H2O : 20 mg/mL (169.29 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Pureté et documentation
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Fiche technique (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Zhang BH, et al., L-valine, an antialgal amino acid from Streptomyces jiujiangensis JXJ 0074(T). Appl Microbiol Biotechnol. 2016 May;100(10):4627-36. [Content Brief]
[2]. Chen XH, et al., Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens. Front Immunol. 2017 Mar 6;8:207. [Content Brief]
[3]. K Kirubavathi, et al. Synthesis, growth, structural, spectroscopic and optical studies of a new semiorganic nonlinear optical crystal: L-valine hydrochloride. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Apr;69(4):1283-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 8.4645 mL | 42.3227 mL | 84.6453 mL | 211.6133 mL |
| 5 mM | 1.6929 mL | 8.4645 mL | 16.9291 mL | 42.3227 mL | |
| 10 mM | 0.8465 mL | 4.2323 mL | 8.4645 mL | 21.1613 mL | |
| 15 mM | 0.5643 mL | 2.8215 mL | 5.6430 mL | 14.1076 mL | |
| 20 mM | 0.4232 mL | 2.1161 mL | 4.2323 mL | 10.5807 mL | |
| 25 mM | 0.3386 mL | 1.6929 mL | 3.3858 mL | 8.4645 mL | |
| 30 mM | 0.2822 mL | 1.4108 mL | 2.8215 mL | 7.0538 mL | |
| 40 mM | 0.2116 mL | 1.0581 mL | 2.1161 mL | 5.2903 mL | |
| 50 mM | 0.1693 mL | 0.8465 mL | 1.6929 mL | 4.2323 mL | |
| 60 mM | 0.1411 mL | 0.7054 mL | 1.4108 mL | 3.5269 mL | |
| 80 mM | 0.1058 mL | 0.5290 mL | 1.0581 mL | 2.6452 mL | |
| 100 mM | 0.0846 mL | 0.4232 mL | 0.8465 mL | 2.1161 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Valine-1-13C Related Classifications
HY-N0717S4 Related Classifications
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