Lactose octaacetate
Based on 1 Customer Validation
Lactose octaacetate (β-Octaacetyllactose) is an Antifungal and antiviral agent. Lactose octaacetate inhibits Aspergillus niger, Penicillium sp., Rhizopus sp., and Fusarium moniliforme. Lactose octaacetate reduces extracellular HSV-1 virions. Lactose octaacetate can be used in research on fungal and viral infections.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 6291-42-5
- Formula: C28H38O19
- Molecular Weight:678.59
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
-
HY-W088070A
Agarose,Low melting pointBiochemical Assay Reagent -
HY-B2123
LactoseMacronutrient -
HY-N10521
6'-SialyllactoseMilk Oligosaccharide -
HY-N10528
3-FucosyllactoseFucosylated Oligosaccharide -
HY-N2024A
Maltose monohydrateDegradative Product of Starch -
HY-W087904
α-Lactose hydrateBiochemical Assay Reagents -
HY-N7575
Lacto-N-fucopentaose IISialyl Lewis Hapten -
HY-B2123R
Lactose (Standard)Macronutrient -
HY-N2024AR
Maltose monohydrate (Standard)Standard of Maltose monohydrate -
HY-N10535
Lewis y tetrasaccharideTumor Antigen -
HY-W087904R
α-Lactose hydrate (Standard)Suger -
HY-N11451
Lacto-N-fucopentaose IIIImmune Modulator
Biological Activity
Description
IC50 & Target
[1]|
HSV-1 |
In Vitro
Lactose octaacetate (24-48 h) showed slight to moderate antifungal activity against Aspergillus niger ATCC 1015, Penicillium sp., Rhizopus sp., and Fusarium moniliforme ATCC 38932, with inhibition zones of 10 mm or 15 mm, but no antibacterial or yeast-inhibitory activity[1].
Lactose octaacetate (15-120 min) reduced extracellular HSV-1 virions, with a Δlog of 1.25 at 15 and 30 min, and a Δlog of 1.50 at 60, 90, and 120 min[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 6291-42-5
-
Appearance Solid
-
Molecular Weight 678.59
-
Formula C28H38O19
-
Color White to off-white
-
SMILES
CC(O[C@H]([C@H]([C@@H](O[C@@H]1COC(C)=O)OC(C)=O)OC(C)=O)[C@@H]1O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(C)=O)OC(C)=O)OC(C)=O)OC(C)=O)=O
-
Synonyms
β-Octaacetyllactose
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (147.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 5 mg/mL (7.37 mM); Clear solution
This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
-
-
-
-
Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
-
%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
-
%+
-
+%Tween-80 + +
-
%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
-
Data Sheet (282 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4736 mL | 7.3682 mL | 14.7364 mL | 36.8411 mL |
| 5 mM | 0.2947 mL | 1.4736 mL | 2.9473 mL | 7.3682 mL | |
| 10 mM | 0.1474 mL | 0.7368 mL | 1.4736 mL | 3.6841 mL | |
| 15 mM | 0.0982 mL | 0.4912 mL | 0.9824 mL | 2.4561 mL | |
| 20 mM | 0.0737 mL | 0.3684 mL | 0.7368 mL | 1.8421 mL | |
| 25 mM | 0.0589 mL | 0.2947 mL | 0.5895 mL | 1.4736 mL | |
| 30 mM | 0.0491 mL | 0.2456 mL | 0.4912 mL | 1.2280 mL | |
| 40 mM | 0.0368 mL | 0.1842 mL | 0.3684 mL | 0.9210 mL | |
| 50 mM | 0.0295 mL | 0.1474 mL | 0.2947 mL | 0.7368 mL | |
| 60 mM | 0.0246 mL | 0.1228 mL | 0.2456 mL | 0.6140 mL | |
| 80 mM | 0.0184 mL | 0.0921 mL | 0.1842 mL | 0.4605 mL | |
| 100 mM | 0.0147 mL | 0.0737 mL | 0.1474 mL | 0.3684 mL |
Lactose octaacetate Related Classifications
HY-W008864 Related Classifications
Powered by Bioz