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Cat. No.: HY-B0614C

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Mafenide propionate

Mafenide propionate is a dual inhibitor of dihydropteroate synthase (Dihydropteroate synthase) and carbonic anhydrase (Carbonic anhydrase). Mafenide propionate disrupts nucleotide biosynthesis by inhibiting the de novo base synthesis pathway, thereby exerting broad-spectrum antibacterial and cytotoxic effects without inducing mutations. Mafenide propionate can be used for wound assessment and promotes the formation of healthy granulation tissue, making it suitable for scenarios such as mesh skin grafting. Mafenide propionate has been widely used in studies on diseases associated with burn wound infections, acute and chronic wounds, blast injuries, open fractures, and necrotizing fasciitis.

For research use only. We do not sell to patients.

CAS No.: 12001-72-8
Formula: C₁₀H₁₆N₂O₄S
Molecular Weight:260.31

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Please store the product under the recommended conditions in the Certificate of Analysis.

Mafenide propionate Chemical Structure

CAS No.: 12001-72-8

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Description

All Carbonic Anhydrase Isoforms :

Chemical Information

CAS No. 12001-72-8
Molecular Weight 260.31
Formula C₁₀H₁₆N₂O₄S
SMILES

O=C(CC)O.O=S(N)(C1=CC=C(CN)C=C1)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Krátký M, et al.. Improving the antimicrobial activity of old antibacterial drug mafenide: Schiff bases and their bioactivity targeting resistant pathogens. Future medicinal chemistry. 2023 Feb;15(3):255-274. [Content Brief]

[2]. Barillo D J. Using mafenide acetate in acute and chronic wounds[J]. OSTOMY WOUND MANAGEMENT, 2002, 48(9; SUPP): 5-10.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Mafenide propionate

All Carbonic Anhydrase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Mafenide propionate Related Classifications

HY-B0614C Related Classifications