MAPK ligand 1
MAPK ligand 1 is an apoptosis inducer and Bcl-xL/MAPK ligand that can be used to synthesize the Bcl-xL-targeted PROTAC degrader (HY-176740). MAPK ligand 1 triggers apoptosis through the mitochondrial pathway, MAPK pathway, reduction of mitochondrial membrane potential and elevation of reactive oxygen species levels. MAPK ligand 1 inhibits colony formation and migration of cancer cells, as well as angiogenesis of endothelial cells. MAPK ligand 1 can be used in the research of hepatocellular carcinoma.
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- CAS No.: 2566503-77-1
- Formule: C20H13NO3
- Masse moléculaire:315.32
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
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Bcl-xL |
Chemical Information
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CAS No. 2566503-77-1
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Masse moléculaire 315.32
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Formule C20H13NO3
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SMILES
OC(C1=CC2=C(NC(C3=CC=CC4=C3C=CC=C4)=CC2=O)C=C1)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MAPK ligand 1 Related Classifications
HY-176741 Related Classifications
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