MEK4 IN-4
MEK4 IN-4 is a MEK4 inhibitor (IC50 = 0.041 μM) that inhibits the kinase catalytic activity of MEK4 via competitive blockade of ATP binding. MEK4 IN-4 can be used to investigate cell proliferative diseases and disorders associated with MEK4 activity, including cancer.
For research use only. We do not sell to patients.
- CAS No.: 2570386-33-1
- Formula: C14H9FN2O2
- Molecular Weight:256.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All MEK Isoforms
More
Biological Activity
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MAP2K4/MEK4 0.041 μM (IC50) |
MEK1 15 μM (IC50) |
MAP2K7/MEK7 12 μM (IC50) |
MEK4 IN-4 (compound 6ff) exhibits inhibitory activity against multiple MEK family subtypes in biochemical assays: it has an IC50 of 0.066 μM against MEK4 (p38), 0.10 μM against MEK4 (Jnk), 15 μM against MEK1, > 27 μM against MEK2, > 27 μM against MEK3, > 27 μM against MEK5, 11 μM against MEK6, and 12 μM against MEK7[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2570386-33-1
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Molecular Weight 256.23
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Formula C14H9FN2O2
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SMILES
O=C(C1=CC=C(C2=C3C=CC(F)=CC3=NN2)C=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MEK4 IN-4 Related Classifications
HY-183856 Related Classifications
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