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Cat. No.: HY-127183

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ML229

ML229 is an HSP90 inhibitor. ML229 can be used in the research of infectious diseases such as candidiasis.

For research use only. We do not sell to patients.

CAS No.: 898918-58-6
Formula: C₁₈H₁₈N₄O₂S
Molecular Weight:354.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

ML229 Chemical Structure

CAS No.: 898918-58-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ML229 is an HSP90 inhibitor. ML229 can be used in the research of infectious diseases such as candidiasis^[1].

IC₅₀ & Target^[1]

HSP90

All HSP Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
NIH3T3	IC₅₀	>26 μM Compound: 3, ML229	Cytotoxicity against mouse 3T3 cells Cytotoxicity against mouse 3T3 cells	[PMID: 22497765]

Chemical Information

CAS No. 898918-58-6
Molecular Weight 354.43
Formula C₁₈H₁₈N₄O₂S
SMILES

O=C1C2=C(C3=C(N2CC(N4CCCC4)=O)C=CC=C3)N=C5SCCN51
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hartland CL, et al. Identification of Small Molecules that Selectively Inhibit Fluconazole-Resistant Candida Albicans in the Presence of Fluconazole but not in its Absence - Probe 3. 2011 Mar 31. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ML229

All HSP Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ML229 Related Classifications

HY-127183 Related Classifications