Morphanthridine
Morphanthridine is a TRPA1 activator with EC50 values of 0.003 μM and 0.083 μM. Morphanthridine is used in pain-related research.
For research use only. We do not sell to patients.
- CAS No.: 256-86-0
- Formula: C14H11N
- Molecular Weight:193.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
hTRPA 0.083 μM (EC50) |
hTRPA 0.003 μM (EC50) |
In Vitro
Morphanthridine is a potent covalent agonist of hTRPA1 heterologously expressed in HEK 293 cells, with an EC50 of 0.003 μM in a Ca2+ fluorescence assay[1].
Morphanthridine activates heterologously expressed h (m) TRPA1 in patch-clamp recordings with an EC50 of 0.083 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 256-86-0
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Molecular Weight 193.24
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Formula C14H11N
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SMILES
C1(C=NC2=CC=CC=C2C3)=C3C=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)