Nervonic acid-d18
Nervonic acid-d18 (Selacholeic acid-d18) is the deuterium labeled Nervonic acid (HY-N2526). Nervonic acid is a monounsaturated fatty acid with oral activity. Nervonic acid exerts anti-inflammatory activity by inhibiting NF-κB signaling. Nervonic acid can be used in the study of neurodegenerative diseases.
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- Formule: C24H28D18O2
- Masse moléculaire:384.73
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 506-37-6
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Masse moléculaire 384.73
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Formule C24H28D18O2
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SMILES
OC(CCCCCCCCCCCCC/C=C(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])(C([2H])([2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])[2H])/[2H])=O
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Synonyms
Selacholeic acid-d18; cis-15-Tetracosenoic acid-d18
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Umemoto H, et al. Protective Effect of Nervonic Acid Against 6-Hydroxydopamine-Induced Oxidative Stress in PC-12 Cells. J Oleo Sci. 2021;70(1):95-102. [Content Brief]
[2]. Hu D, et al. Nervonic acid amends motor disorder in a mouse model of Parkinson's disease. Transl Neurosci. 2022 Apr 20;13(1):71. [Content Brief]
[3]. Yuan SN, et al. Improved colonic inflammation by nervonic acid via inhibition of NF-κB signaling pathway of DSS-induced colitis mice. Phytomedicine. 2023 Apr;112:154702. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nervonic acid-d18 Related Classifications
HY-W746544 Related Classifications
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