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Cat. No.: HY-B1159R

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Nitroxoline (Standard)

(Synonyms: 8-Hydroxy-5-nitroquinoline (Standard); 5-Nitro-8-quinolinol (Standard))

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Nitroxoline (Standard) is the analytical standard of Nitroxoline. This product is intended for research and analytical applications. Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research.

For research use only. We do not sell to patients.

Purity: 99.64%
CAS No.: 4008-48-4
Formula: C₉H₆N₂O₃
Molecular Weight:190.16

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Nitroxoline (Standard) Chemical Structure

CAS No.: 4008-48-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Product Information
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Chemical Information
Purity & Documentation
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Bioz

Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 4008-48-4
Appearance Solid
Molecular Weight 190.16
Formula C₉H₆N₂O₃
Color Light brown to brown
SMILES

OC1=C2N=CC=CC2=C([N+]([O-])=O)C=C1
Synonyms

8-Hydroxy-5-nitroquinoline (Standard); 5-Nitro-8-quinolinol (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. A Sobke, et al. The urinary antibiotic 5-nitro-8-hydroxyquinoline (Nitroxoline) reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Antimicrob Agents Chemother. 2012 Nov;56(11):6021-5. [Content Brief]

[2]. Jin-Guo Yu, et al. Nitroxoline induces cell apoptosis by inducing MDM2 degradation in small-cell lung cancer. Kaohsiung J Med Sci. 2019 Apr;35(4):202-208. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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