PBA-AMF
PBA-AMF can be activated by H2O2 to release Amonafide (AMF) (HY-10982). PBA-AMF selectively inhibited the proliferation of breast cancer cells, while sparing non-cancerous cells. PBA-AMF inhibits tumor proliferation by inhibiting DNA synthesis, reducing ATP levels, inducing apoptosis, and arresting the cell cycle. PBA-AMF can be used for research of tumors and other diseases associated with increased H2O2 levels.
For research use only. We do not sell to patients.
- Formula: C24H24BN3O6
- Molecular Weight:461.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Biological Activity
Chemical Information
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Molecular Weight 461.27
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Formula C24H24BN3O6
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SMILES
O=C(C1=CC(NC(OCC2=CC=C(B(O)O)C=C2)=O)=CC3=C1C4=CC=C3)N(CCN(C)C)C4=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PBA-AMF Related Classifications
HY-159560 Related Classifications
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