Rabeximod
Rabeximod (ROB-803), an anti-rheumatic compound, impairs the differentiation and function of human pro-inflammatory dendritic cells and macrophages via downregulating TLR2 and TLR4 stimulation. Rabeximod (ROB-803) is used for rheumatoid arthritis (RA) research.
For research use only. We do not sell to patients.
- CAS No.: 872178-65-9
- Formula: C22H24ClN5O
- Molecular Weight:409.91
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
TLR2 |
TLR4 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 872178-65-9
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Molecular Weight 409.91
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Formula C22H24ClN5O
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SMILES
O=C(CN1C2=NC3=C(N=C2C4=C1C=CC(Cl)=C4)C=C(C)C(C)=C3)NCCN(C)C
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Synonyms
ROB-803
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)