1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. NSC639828

NSC639828 

Cat. No.: HY-145330 Purity: 99.91%
Handling Instructions

NSC639828 is a potent inhibitor of DNA polymerase α with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease.

For research use only. We do not sell to patients.

NSC639828 Chemical Structure

NSC639828 Chemical Structure

CAS No. : 134742-26-0

Size Price Stock Quantity
5 mg USD 400 In-stock
Estimated Time of Arrival: December 31
10 mg USD 680 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 2200 In-stock
Estimated Time of Arrival: December 31
100 mg USD 3500 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

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  • Customer Review

Description

NSC639828 is a potent inhibitor of DNA polymerase α with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for researching cancer disease[1].

IC50 & Target

DNA polymerase α[1].

Molecular Weight

462.68

Formula

C18H13BrClN5O3

CAS No.
SMILES

O=C(NC1=CC=C(C(Cl)=C1)OC2=NC=C(C=N2)Br)NC(C3=C(N)C=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (216.13 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1613 mL 10.8066 mL 21.6132 mL
5 mM 0.4323 mL 2.1613 mL 4.3226 mL
10 mM 0.2161 mL 1.0807 mL 2.1613 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.40 mM); Clear solution

*All of the co-solvents are available by MCE.
References

Purity: 99.91%

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Product Name:
NSC639828
Cat. No.:
HY-145330
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