P-gp inhibitor 23
P-gp inhibitor 23 (compound 14F) is a potent inhibitor of P-gp and CYP3A4, with the EC50 and IC50 of 28 nM and 223 nM, respectively.
For research use only. We do not sell to patients.
- Formula: C40H37N5O6
- Molecular Weight:683.75
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
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CYP3A4 |
Chemical Information
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Molecular Weight 683.75
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Formula C40H37N5O6
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SMILES
COC1=C(C=C(C(NC(C2=CC(C3=C(O2)C=CC=C3)=O)=O)=C1)C(NC4=CC=C(C=C4)C5CCN(CC6=CC(N7C=CN=C7)=CC=C6)CC5)=O)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
P-gp inhibitor 23 Related Classifications
HY-158435 Related Classifications
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