Paclitaxel ceribate
Paclitaxel ceribate is the ester form of paclitaxel, a natural antineoplastic agent that stabilizes tubulin polymerization. Paclitaxel causes mitotic arrest and induces apoptosis, ultimately leading to cell death. Paclitaxel also induces autophagy.
For research use only. We do not sell to patients.
- CAS No.: 186040-50-6
- Formula: C51H57NO18
- Molecular Weight:971.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 186040-50-6
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Molecular Weight 971.99
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Formula C51H57NO18
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SMILES
CC(O[C@]12[C@]([C@@H]3OC(C4=CC=CC=C4)=O)([H])[C@@]([C@@H](OC(OCC(O)CO)=O)C[C@@]1([H])OC2)(C([C@@H](C5=C(C)[C@@H](OC([C@H](O)[C@H](C6=CC=CC=C6)NC(C7=CC=CC=C7)=O)=O)C[C@]3(O)C5(C)C)OC(C)=O)=O)C)=O
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Synonyms
Protaxel
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Choi YH, et al. Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells. Oncol Rep. 2012 Dec;28(6):2163-9. [Content Brief]
[2]. Dziadyk JM, et al. Paclitaxel-induced apoptosis may occur without a prior G2/M-phase arrest. Anticancer Res. 2004 Jan-Feb;24(1):27-36. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)