PARP7-IN-25
PARP7-IN-25 is a PARP7 inhibitor with an IC50 of 1.582 nM.PARP7-IN-25 inhibits enzymatic activity of PARP7. PARP7-IN-25 inhibits proliferation of lung cancer cells.PARP7-IN-25 can be used for the research of PARP7-related cancer.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 2819998-77-9
- 화학식: C23H23F6N5O4
- 분자량:547.45
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocol
- 순도&문서
- References
-
Help & FAQs
Biological Activity
제품 설명
IC50 & Target
[1]|
PARP7 1.582 nM (IC50) |
In Vitro
PARP7-IN-25 (compound I) (0.08-50 nM; 15 min pre-incubation, 3 h final incubation at 25°C) potently inhibits recombinant PARP7 enzyme activity with an IC50 of 1.582 nM[1].
PARP7-IN-25 (144 h) potently inhibits the proliferation of PARP7-overexpressing H1373 lung cancer cells with an IC50 of 13.012 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2819998-77-9
-
분자량 547.45
-
화학식 C23H23F6N5O4
-
SMILES
CC1=C2N(CCN(C2)C(CCOC[C@H](C)OC3=C(C(NN=C3)=O)C(F)(F)F)=O)C4=NC=C(C(F)(F)F)C=C41
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PARP7-IN-25 Related Classifications
HY-179312 Related Classifications
Powered by Bioz