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PCA-IN-1

PCA-IN-1 is a polyisoprenylated cysteinyl amide (PCA) inhibitor that acts on multiple KRAS mutant subtypes. PCA-IN-1 dissociates KRAS4B from its transport chaperones, prevents its localization to the plasma membrane, and blocks downstream oncogenic signaling pathways. PCA-IN-1 inhibits colony formation of KRAS-mutant lung cancer cells, induces sustained long-term growth inhibition, and suppresses cell migration. PCA-IN-1 is applicable to the research of KRAS-mutant lung cancer.

For research use only. We do not sell to patients.

  • Formula: C33H58N4O2S
  • Molecular Weight:574.90
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • PCA-IN-1 Chemical Structure
    PCA-IN-1 Chemical Structure
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All Ras Isoforms

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  • PCA-IN-1 Chemical Structure
    PCA-IN-1 Chemical Structure
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  • PCA-IN-1