PI3Kδ-IN-12
PI3Kδ-IN-12 (compound 13) is a PI3Kδ inhibitor (pIC50 = 5.8), with pKi values of 8.0/6.5/6.4/6.7 for PI3Kδ/γ/β/α, respectively. PI3Kδ-IN-12 can be used in the study of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).
For research use only. We do not sell to patients.
- Formula: C20H15Cl2N5O3
- Molecular Weight:444.27
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
PI3Kδ 5.8 (pIC50) |
PI3Kδ 8.0 (pKi) |
PI3Kγ 6.5 (pKi) |
PI3Kβ 6.4 (pKi) |
PI3Kα 6.7 (pKi) |
Chemical Information
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Molecular Weight 444.27
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Formula C20H15Cl2N5O3
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SMILES
NC(C1=C2NC(N(C2=NC(C3=CC(O)=CC=C3)=N1)CCC4=CC=C(C(Cl)=C4)Cl)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)