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Cat. No.: HY-163862

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PPARα agonist 3

PPARα agonist 3 (Compound A229) is a PPARα agonist (EC₅₀: 590 nM). PPARα agonist 3 inhibits TBHP or 4-HNE (HY-113466)-induced production of ROS.

For research use only. We do not sell to patients.

Formula: C₂₀H₁₅F₂NO₂
Molecular Weight:339.34

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

PPARα agonist 3 Chemical Structure

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Quantity

Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PPARα agonist 3 (Compound A229) is a PPARα agonist (EC₅₀: 590 nM). PPARα agonist 3 inhibits TBHP or 4-HNE (HY-113466)-induced production of ROS^[1].

All PPAR Isoforms :

Chemical Information

Molecular Weight 339.34
Formula C₂₀H₁₅F₂NO₂
SMILES

O=C(O)C1=CC(NCC2=CC=C(C3=CC=C(F)C=C3)C=C2)=CC(F)=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bo Hu, et al. Design and Assessment of First-Generation Heterobifunctional PPARα/STING Modulators. ACS Medicinal Chemistry Letters Article ASAP

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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