BRD4 degrader-4
BRD4 degrader-4 (Compound 1-f) is a BRD4 degrader. BRD4 degrader-4 can be used for the research of cancer and other bromodomain related diseases.
For research use only. We do not sell to patients.
- CAS No.: 2851986-83-7
- Formula: C34H30FN9O2S
- Molecular Weight:647.72
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
In Vitro
BRD4 degraders are small molecule compounds that specifically target the BRD4 protein and induce its degradation via the ubiquitin-proteasome or autophagy-lysosome pathway. They can selectively reduce intracellular BRD4 protein levels without affecting mRNA expression and are used in research on diseases related to bromodomain proteins and in the development of anticancer drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2851986-83-7
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Molecular Weight 647.72
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Formula C34H30FN9O2S
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SMILES
CC1=C(C)SC2=C1C(C3=CC=C(C4=CC(NC(C5=C6N(C=CC=N6)N=C5)=O)=C(C=C4)F)C=C3)=N[C@@H](CC(N(C)C)=O)C7=NN=C(C)N27
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)