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Cat. No.: HY-160527

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BRD4 degrader-4

BRD4 degrader-4 (Compound 1-f) is a BRD4 degrader. BRD4 degrader-4 can be used for the research of cancer and other bromodomain related diseases.

For research use only. We do not sell to patients.

CAS No.: 2851986-83-7
Formula: C₃₄H₃₀FN₉O₂S
Molecular Weight:647.72

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (282 KB)

BRD4 degrader-4 Chemical Structure

CAS No.: 2851986-83-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

BRD4 degrader-4 (Compound 1-f) is a BRD4 degrader. BRD4 degrader-4 can be used for the research of cancer and other bromodomain related diseases^[1].

All Epigenetic Reader Domain Isoforms :

In Vitro

The core of proliferative diseases is the abnormal increase in cell number. The phenomenon in which active cell mitosis leads to an increased number of cells within a tissue or organ is called proliferation. This typically results in organ enlargement, and it may be either a normal physiological adaptation or a disease state requiring intervention.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2851986-83-7
Molecular Weight 647.72
Formula C₃₄H₃₀FN₉O₂S
SMILES

CC1=C(C)SC2=C1C(C3=CC=C(C4=CC(NC(C5=C6N(C=CC=N6)N=C5)=O)=C(C=C4)F)C=C3)=N[C@@H](CC(N(C)C)=O)C7=NN=C(C)N27
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (282 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Bailey S, et al. Preparation of aminobiarylthienotriazolodiazepinylacetamide derivatives for use as BRD4 modulators. WO2022221786A2. 2022-10-20.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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