PROTAC HDAC8 Degrader-2
PROTAC HDAC8 Degrader-2 (compound 32a) is a degrader of HDAC8 with a DC50 of 8.9 nM and HDAC6 with a DC50 of 14.3 nM.
(Pink: HDAC8 ligand (HY-103596); Blue: Cereblon ligand (HY-103596); Black: linker).
For research use only. We do not sell to patients.
- Formula: C39H44N10O8
- Molecular Weight:780.83
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
More
Biological Activity
|
HDAC8 8.9 nM (DC50) |
Chemical Information
-
Molecular Weight 780.83
-
Formula C39H44N10O8
-
SMILES
O=C(C1=CN=C(N2CCN(CC3=CN(C)C4=C3C=C(OCC(NCCCCCNC5=CC=CC(C(N6C(CC7)C(NC7=O)=O)=O)=C5C6=O)=O)C=C4)CC2)N=C1)NO
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)