PROTAC SMARCA2 degrader-31
PROTAC SMARCA2-degrader-36 (compound 38) is a SMARCA2 degrader and can reach the the degradation rate of 99 % at the 100 nM in H929 cells. PROTAC SMARCA2-degrader-36 shows anti-proliferative activity and can be used for study of cancer(Structure Note: PINK SMARCA2 ligand HY-44012; Blue, VHL ligand (HY-112078); Black, linker HY-W014125).
(Pink: SMARCA2 ligand (HY-44012); Blue: VHL ligand (HY-112078); Black: linker (HY-W014125)).
For research use only. We do not sell to patients.
- CAS No.: 2380274-45-1
- Formula: C48H65N9O6S
- Molecular Weight:896.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 2380274-45-1
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Molecular Weight 896.15
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Formula C48H65N9O6S
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SMILES
OC1=C(C2=CC(N3CCN(C(CCCCCCCCCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)C[C@@H](O)C4)=O)=O)=O)CC3)=C(N)N=N2)C=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PROTAC SMARCA2 degrader-31 Related Classifications
HY-168234 Related Classifications
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