1. Recombinant Proteins
  2. Cytokines and Growth Factors
  3. Interferon & Receptors
  4. IFN-alpha
  5. IFN-alpha 2a

IFN-alpha 2 (IFNA2; IFN-α2), belongs to the type I interferon family, produced by produced by the plasmacytoid dendritic cells (pDCs) exposure to HIV-1BaL in order to inhibit viral infection[1]. Interferon (IFN) is originally identified as a substance ‘interfering’ with viral replication in vitro. IFN-α/β and related molecules are classified as type I IFNs, as for the other two types of type II IFN (IFN-γ) and type III IFNs (IFN-λ), respectively[2].
IFN-alpha 2 subtype is the only one that is currently licensed to treat infections caused by hepatitis B virus (HBV) and HCV[3]. IFN-alpha 2 shows a Sortilin-dependent trafficking in cells and increases the expression level of interferon-stimulated genes (ISGs) in HIV-infected cells[1][4]. It also exhibits cytotoxic activity against CD8+ T cells and enhances CD4+ T cell depletion[3].
Among the IFN-alpha 2 alleles, IFN-alpha 2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant[5]. IFN-alpha 2 has a bored application in research of cancer, including some hematological malignancies and solid tumors[6].

Cat. No. Product Name / Synonyms Species Source
  • HY-P78552
    GMP IFN-gamma Protein, Human

    Interferon Gamma; IFN-Gamma; Immune Interferon; IFNG

    Human E. coli
    IFN-gamma Protein is a dimeric soluble cytokine. It exerts antibacterial, antiviral and antitumor effects through JAK-STAT, mTOR, MAPK and PI3K/AKT signaling pathways. GMP IFN-gamma Protein, Human is the recombinant human-derived IFN-gamma protein, expressed by E. coli , with tag free. The total length of GMP IFN-gamma Protein, Human is 143 a.a., with molecular weight of ~16.7 kDa.
  • HY-P73246
    IFN-alpha 2/IFNA2 Protein, Human (P.pastoris)

    Interferon alpha-2; IFN-alpha-2; LeIF A; IFNA2; IFNA2A

    Human P. pastoris
    IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8+ T cells and induces CD4+ T cell depletion. IFN-alpha 2/IFNA2 Protein, Human (P.pastoris) contains 165 a.a., is produced in yeast strain P. pastoris with tag free.
  • HY-P7022
    IFN-alpha 2a/IFNA2 Protein, Human (R46K)

    rHuIFN-α2a; IFNA; IFNA2; IFN-a 2a

    Human E. coli
    IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8+ T cells and induces CD4+ T cell depletion. IFN-alpha 2a/IFNA2 Protein, Human (C24-E188, R46K) contains 165 a.a., is produced in E. coli with tag free.
  • HY-P73247
    IFN-alpha 2/IFNA2 Protein, Mouse (P.pastoris)

    Interferon alpha-2; IFN-alpha-2; LeIF A; IFNA2; IFNA2A

    Mouse P. pastoris
    IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8+ T cells and induces CD4+ T cell depletion. IFN-alpha 2/IFNA2 Protein, Mouse (P.pastoris) contains 167 a.a. (C24-E190), is produced in yeast strain P. pastoris with tag free.
  • HY-P73248
    IFN-alpha 2/IFNA2 Protein, Mouse (HEK293, Fc)

    Interferon alpha-2; IFN-alpha-2; LeIF A; IFNA2; IFNA2A

    Others HEK293
    IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8+ T cells and induces CD4+ T cell depletion. IFN-alpha 2/IFNA2 Protein, Mouse (HEK293, Fc) contains 167 a.a. (C24-E190), is produced in HEK293 cells with a N-terminal hFc-tag.
  • HY-P75890
    IFN-alpha 2/IFNA2 Protein, Rhesus Macaque (HEK293, His)

    Interferon alpha-2; IFN-alpha-2; Interferon alpha-A; LeIF A; IFNA2A

    Rhesus Macaque HEK293
    IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8+ T cells and induces CD4+ T cell depletion. IFN-alpha 2/IFNA2 Protein, Rhesus Macaque (HEK293, His) contains 188 a.a. (M1-E188), is produced in HEK293 cells with a C-terminal His-tag.
  • HY-P7544
    IFN-alpha 2/IFNA2 Protein, Mouse

    Interferon alpha 2; IFNA2 Protein, Mouse

    Mouse E. coli
    IFN-alpha 2/IFNA2 Protein, synthesized by macrophages, exhibits potent antiviral activities. Its interaction with IFNAR2 plays a pivotal role in signaling processes, contributing to the intricate network of antiviral defense mechanisms. IFN-alpha 2/IFNA2 Protein, Mouse is the recombinant mouse-derived IFN-alpha 2/IFNA2 protein, expressed by E. coli , with tag free. The total length of IFN-alpha 2/IFNA2 Protein, Mouse is 167 a.a., with molecular weight of 16-20 kDa.
  • HY-P7544A
    IFN-alpha 2/IFNA2 Protein, Mouse (His)

    Interferon alpha 2; IFNA2 Protein, Mouse

    Mouse E. coli
    IFN-alpha 2/IFNA2 Protein, synthesized by macrophages, exhibits potent antiviral activities. Its interaction with IFNAR2 plays a pivotal role in signaling processes, contributing to the intricate network of antiviral defense mechanisms. IFN-alpha 2/IFNA2 Protein, Mouse (His) is the recombinant mouse-derived IFN-alpha 2/IFNA2 protein, expressed by E. coli , with N-6*His labeled tag. The total length of IFN-alpha 2/IFNA2 Protein, Mouse (His) is 167 a.a., with molecular weight of ~20 kDa.
  • HY-P75891
    IFN-alpha 2/IFNA2 Protein, Rhesus Macaque (HEK293, Fc)

    Interferon alpha-2; IFN-alpha-2; Interferon alpha-A; LeIF A; IFNA2A

    Rhesus Macaque HEK293
    IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8+ T cells and induces CD4+ T cell depletion. IFN-alpha 2/IFNA2 Protein, Rhesus Macaque (HEK293, Fc) contains 188 a.a. (M1-E188), is produced in HEK293 cells with a C-terminal mFc-tag.
  • HY-P75889
    IFN-alpha 2/IFNA2 Protein, Rhesus Macaque (P.pastoris)

    Interferon alpha-2; IFN-alpha-2; Interferon alpha-A; LeIF A; IFNA2A

    Rhesus Macaque P. pastoris
    IFN-alpha 2 (IFNA2), belongs to type I interferon family, is a protein secreted by cells infected by a virus and acting on other cells to inhibit viral infection. IFN-alpha 2 exerts cytotoxic activity against CD8+ T cells and induces CD4+ T cell depletion. IFN-alpha 2/IFNA2 Protein, Rhesus Macaque (P.pastoris) contains 165 a.a. (C24-E188), is produced in yeast strain P. pastoris with tag free.
Cat. No. Product Name Effect Purity