PythiDC
Based on 1 Customer Validation
PythiDC is a selective collagen prolyl 4-hydroxylase (CP4H1) inhibitor with an IC50 value of 4.0 μM. PythiDC can be used as a CP4H probe and also can be used for the development of a new class of antifibrotic and antimetastatic agents.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.05%
- CAS 番号: 1821370-71-1
- 分子式: C10H6N2O4S
- 分子量:250.23
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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HY-103068
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TAPI-2MMP/TACE/ADAM Inhibitor
生物活性
製品説明
化学情報
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CAS 番号 1821370-71-1
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性状 Solid
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分子量 250.23
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分子式 C10H6N2O4S
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Color White to off-white
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SMILES
O=C(C1=CC=C(C2=NC=C(C(O)=O)S2)N=C1)O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
1 M NaOH : 50 mg/mL (199.82 mM; Need ultrasonic)
DMSO : 4.9 mg/mL (19.58 mM; ultrasonic and warming and adjust pH to 4 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
プロトコル
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
純度とドキュメンテーション
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データシート (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / 1 M NaOH | 1 mM | 3.9963 mL | 19.9816 mL | 39.9632 mL | 99.9081 mL |
| 5 mM | 0.7993 mL | 3.9963 mL | 7.9926 mL | 19.9816 mL | |
| 10 mM | 0.3996 mL | 1.9982 mL | 3.9963 mL | 9.9908 mL | |
| 15 mM | 0.2664 mL | 1.3321 mL | 2.6642 mL | 6.6605 mL | |
| 1 M NaOH | 20 mM | 0.1998 mL | 0.9991 mL | 1.9982 mL | 4.9954 mL |
| 25 mM | 0.1599 mL | 0.7993 mL | 1.5985 mL | 3.9963 mL | |
| 30 mM | 0.1332 mL | 0.6661 mL | 1.3321 mL | 3.3303 mL | |
| 40 mM | 0.0999 mL | 0.4995 mL | 0.9991 mL | 2.4977 mL | |
| 50 mM | 0.0799 mL | 0.3996 mL | 0.7993 mL | 1.9982 mL | |
| 60 mM | 0.0666 mL | 0.3330 mL | 0.6661 mL | 1.6651 mL | |
| 80 mM | 0.0500 mL | 0.2498 mL | 0.4995 mL | 1.2489 mL | |
| 100 mM | 0.0400 mL | 0.1998 mL | 0.3996 mL | 0.9991 mL |
PythiDC 関連分類
HY-103070 関連分類
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