1. Immunology/Inflammation
  2. COX
  3. Robenacoxib

Robenacoxib is a nonsteroidal anti-inflammatory and analgesic agent. Robenacoxib is a selective COX-2 inhibitor.

For research use only. We do not sell to patients.

Robenacoxib Chemical Structure

Robenacoxib Chemical Structure

CAS No. : 220991-32-2

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5 mg USD 185 In-stock
10 mg USD 300 In-stock
25 mg USD 580 In-stock
50 mg USD 920 In-stock
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Description

Robenacoxib is a nonsteroidal anti-inflammatory and analgesic agent. Robenacoxib is a selective COX-2 inhibitor[1][2].

Molecular Weight

327.27

Formula

C16H13F4NO2

CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(CC1=CC(CC)=CC=C1NC2=C(C(F)=CC(F)=C2F)F)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (381.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0556 mL 15.2779 mL 30.5558 mL
5 mM 0.6111 mL 3.0556 mL 6.1112 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0556 mL 15.2779 mL 30.5558 mL 76.3895 mL
5 mM 0.6111 mL 3.0556 mL 6.1112 mL 15.2779 mL
10 mM 0.3056 mL 1.5278 mL 3.0556 mL 7.6390 mL
15 mM 0.2037 mL 1.0185 mL 2.0371 mL 5.0926 mL
20 mM 0.1528 mL 0.7639 mL 1.5278 mL 3.8195 mL
25 mM 0.1222 mL 0.6111 mL 1.2222 mL 3.0556 mL
30 mM 0.1019 mL 0.5093 mL 1.0185 mL 2.5463 mL
40 mM 0.0764 mL 0.3819 mL 0.7639 mL 1.9097 mL
50 mM 0.0611 mL 0.3056 mL 0.6111 mL 1.5278 mL
60 mM 0.0509 mL 0.2546 mL 0.5093 mL 1.2732 mL
80 mM 0.0382 mL 0.1910 mL 0.3819 mL 0.9549 mL
100 mM 0.0306 mL 0.1528 mL 0.3056 mL 0.7639 mL
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Robenacoxib Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Robenacoxib
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HY-118078
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