RORγ-IN-3
RORγ-IN-3 (Compound 21) is a potent and highly selective RORγ inhibitor with an EC50 of 84 nM. RORγ-IN-3 can effectively inhibit the production of IL-17, with an IC₅₀ value of 1.0 μM. RORγ-IN-3 can be used for the study of autoimmune diseases.
For research use only. We do not sell to patients.
- Formula: C19H27ClN2O2
- Molecular Weight:350.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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ROR-γ 84 nM (EC50) |
IL-17 1 μM (IC50) |
Chemical Information
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Molecular Weight 350.88
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Formula C19H27ClN2O2
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SMILES
ClC1=C(OCC(C)(C)C)C=CC(C2C(C(C)(C)C)=CNC(N2)=O)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)