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Runimotamab

(Synonyms: BTRC-4017A; RG-6194)
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Based on 1 Customer Validation

Runimotamab (BTRC-4017A) is a HER2 and CD3 T cell-engaging bispecific antibody. Runimotamab can decrease the size of liver tumor spheroids. Runimotamab can be studied in oncology research such as HER2-expressing cancers. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).

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  • Pureté: 99.00%
  • CAS No.: 2361325-98-4
  • Masse moléculaire:146.081 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Runimotamab
  • Experimental Validation Results for Runimotamab
  • Experimental Validation Results for Runimotamab
  • Experimental Validation Results for Runimotamab
  • Runimotamab Chemical Structure
    Runimotamab Chemical Structure
CAS No.: 2361325-98-4
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Runimotamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Runimotamab (HY-P99896). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • 1/16

    Loaded Runimotamab on AHC2 biosensor, can bind Her2/CD340 Protein, Human (Biotinylated, HEK293, His, HY-P78882) with an affinity constant of 2.473E-10 M as determined in BLI assay.

  • 1/16

    Loaded Runimotamab on AHC2 biosensor, can bind CD3 epsilon Protein, Human (HEK293, His, HY-P70506) with an affinity constant of 1.122E-10 M as determined in BLI assay.

  • Runimotamab Chemical Structure
    1/16
  • Runimotamab
  • Flow cytometric analysis of 1×106 Jurkat cells labelling CD3E (red) with Runimotamab (HY-P99896). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
  • Loaded Runimotamab on AHC2 biosensor, can bind Her2/CD340 Protein, Human (Biotinylated, HEK293, His, HY-P78882) with an affinity constant of 2.473E-10 M as determined in BLI assay.
  • Loaded Runimotamab on AHC2 biosensor, can bind CD3 epsilon Protein, Human (HEK293, His, HY-P70506) with an affinity constant of 1.122E-10 M as determined in BLI assay.