Salviifoside A 

Salviifoside A is a phenolic glycoside found in the leaves of Alangium salviifolium. Salviifoside A inhibits LPS (HY-D1056)-induced nitric oxide and prostaglandin E₂ production in macrophages without affecting cell viability^[1].

Salviifoside A (5-50 μM; 1 h pretreatment, 24 h post-LPS stimulation) dose-dependently inhibits LPS-induced NO production in RAW 264.7 cells, with significant inhibition observed at 25 and 50 μM^[1].
Salviifoside A (5-50 μM; 1 h pretreatment, 24 h post-LPS stimulation) dose-dependently inhibits LPS-induced PGE₂ production in RAW 264.7 cells, with significant inhibition observed at 25 and 50 μM^[1].
Salviifoside A (5-50 μM; 24 h (with or without LPS co-treatment)) shows no cytotoxicity against RAW 264.7 cells at concentrations up to 50 μM after 24 h of incubation, with or without LPS stimulation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

406.38

C₂₀H₂₂O₉

1175539-71-5

OC[C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC2=C(C=C(C=C2)COC(C3=CC=CC=C3)=O)O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Tran MH, et al. Phenolic glycosides from Alangium salviifolium leaves with inhibitory activity on LPS-induced NO, PGE(2), and TNF-alpha production. Bioorg Med Chem Lett. 2009;19(15):4389-4393.  [Content Brief]