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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
235 Results for "
low-affinity
" in MedChemExpress (MCE) Product Catalog:
Products (235)
235 Results for "low-affinity" in MCE Product Catalog:
Cat. No.: HY-P77101
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: NGFR; low affinity Neurotrophin Receptor P75NTR; Nerve Growth Factor Receptor; TNFR Superfamily, Member 16; TNFRSF16; NGF Receptor; P75NTR; Gp80-LNGFR; CD271; P75 ICD; Tumor Necrosis Factor Receptor Superfamily Member 16; Nerve Growth Factor Receptor (TNF
Species:
Mouse
Source:
HEK293
Cat. No.: HY-124356AS
Cat. No.: HY-D1447
CAS No.: 348079-14-1
Cat. No.: HY-D1755
CAS No.: 348079-13-0
Cat. No.: HY-P11813
CAS No.: 160662-30-6
Target:
Research Areas:
Cat. No.: HY-P87429A
Synonyms: CD16b, CD16B, FCG3, FCGR3, IGFR3, FCGR3B, low affinity immunoglobulin gamma Fc region receptor III-B, Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, CD16-I, Fc-gamma RIII, Fc-gamma RIIIb, FcRIII, FcRIIIb
Cat. No.: HY-P72748
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCER2; Immunoglobulin E-Binding Factor; Prev. CD23A; Lymphocyte IgE Receptor; Prev. FCE2; Fc-Epsilon-RII; CLEC4J; BLAST-2; FcepsilonRII; IGEBF; CD23 Antigen; Fc Fragment Of IgE, low affinity II, Receptor For (CD23A); FCErII; C-Type Lectin Domain Family 4,
Species:
Human
Source:
HEK293
Cat. No.: HY-P74320
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCER2; Immunoglobulin E-Binding Factor; Prev. CD23A; Lymphocyte IgE Receptor; Prev. FCE2; Fc-Epsilon-RII; CLEC4J; BLAST-2; FcepsilonRII; IGEBF; CD23 Antigen; Fc Fragment Of IgE, low affinity II, Receptor For (CD23A); FCErII; C-Type Lectin Domain Family 4,
Species:
Rat
Source:
HEK293
Cat. No.: HY-P74321
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FCER2; Immunoglobulin E-Binding Factor; Prev. CD23A; Lymphocyte IgE Receptor; Prev. FCE2; Fc-Epsilon-RII; CLEC4J; BLAST-2; FcepsilonRII; IGEBF; CD23 Antigen; Fc Fragment Of IgE, low affinity II, Receptor For (CD23A); FCErII; C-Type Lectin Domain Family 4,
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P81202
Synonyms: FCG3A_HUMAN; low affinity immunoglobulin gamma Fc region receptor III-A; CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD_antigen: D16a; FCGR3A; CD16A; FCG3; FCGR3; IGFR3.
Cat. No.: HY-P811546
Synonyms: FCG3A_HUMAN; low affinity immunoglobulin gamma Fc region receptor III-A; CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2; CD_antigen: D16a; FCGR3A; CD16A; FCG3; FCGR3; IGFR3.
Cat. No.: HY-186083
CAS No.: 36167-80-3
Target:
Research Areas:
Propylbenzilylcholine mustard (PrBCM) is an irreversible, covalently binding selective antagonist targeting rat cardiac muscarinic receptors, with a preference for muscarinic receptor subtypes that show low affinity for agonists. Propylbenzilylcholine mustard inactivates such receptors in a dose- and time-dependent manner in vitro, and its receptor selectivity remains stable across different ionic strengths and in GTP-containing buffer systems. Propylbenzilylcholine mustard can be applied to basic pharmacological studies on the structure and function of muscarinic receptors, especially focusing on the heterogeneity of cardiac muscarinic receptors and related cardiovascular pharmacological research .
Cat. No.: HY-B1562
CAS No.: 62658-63-3
Synonyms: (±)-Bopindolol
Target:
Research Areas:
Bopindolol ((±)-Bopindolol) is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol is a proagent of Pindolol (HY-B0982). Bopindolol can be used for essential and renovascular hypertension research.
Cat. No.: HY-B1562C
CAS No.: 79125-22-7
Synonyms: (±)-Bopindolol fumarate
Target:
Research Areas:
Bopindolol ((±)-Bopindolol) fumarate is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol fumarate is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol fumarate has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol fumarate is a proagent of Pindolol (HY-B0982). Bopindolol fumarate can be used for essential and renovascular hypertension research.
Cat. No.: HY-P10762
CAS No.: 2082631-84-1
Synonyms: CBP-1008; LDC 10B
Research Areas:
Cat. No.: HY-U00050
CAS No.: 47132-16-1
Synonyms: E-10-OH-NT
Target:
Research Areas:
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a blood-brain barrier-permeable norepinephrine uptake inhibitor. (E)-10-Hydroxynortriptyline effectively promotes central norepinephrine neuronal transmission, with little interindividual variation in in vivo potency. (E)-10-Hydroxynortriptyline has low affinity for muscarinic receptors, exhibits only extremely weak anticholinergic activity, and does not inhibit salivary secretion. (E)-10-Hydroxynortriptyline can be used in studies related to depression .
Cat. No.: HY-117160
CAS No.: 23155-00-2
Synonyms: 4-trans-hydroxycyclohexyl Glyburide; 4-trans-hydroxy Glibenclamide
Target:
Research Areas:
rac-trans-4-hydroxy Glyburide is an active metabolite of the SUR1/Kir6.2 sulfonylurea inhibitor glyburide (HY-15206). It is formed from glyburide by the cytochrome P450 (CYP) isoforms CYP2C8 and CYP2C9. rac-trans-4-hydroxy Glyburide inhibits glyburide binding to rat brain synaptosomes at the high and low affinity sites of SUR1/Kir6.2 with IC50 values of 0.95 and 100 nM, respectively.
Cat. No.: HY-B1562B
CAS No.: 82857-38-3
Synonyms: (±)-Bopindolol malonate
Target:
Research Areas:
Bopindolol ((±)-Bopindolol) malonate is an orally active antagonist of β-adrenoceptors (ARs) with partial agonist activity. Bopindolol malonate is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol malonate has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibits renin secretion, and interacts with 5-HT receptors. Bopindolol malonate is a proagent of Pindolol (HY-B0982). Bopindolol malonate can be used for essential and renovascular hypertension research.
Cat. No.: HY-P703986
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: FCER2; Immunoglobulin E-Binding Factor; Prev. CD23A; Lymphocyte IgE Receptor; Prev. FCE2; Fc-Epsilon-RII; CLEC4J; BLAST-2; FcepsilonRII; IGEBF; CD23 Antigen; Fc Fragment Of IgE, low affinity II, Receptor For (CD23A); FCErII; C-Type Lectin Domain Family 4,
Species:
Human
Source:
HEK293
Cat. No.: HY-118990
CAS No.: 246244-19-9
Target:
Research Areas:
Lobelane hydrochloride is a biologically active compound that has the activity of inhibiting vesicular monoamine transporter-2 (VMAT2). Lobelane hydrochloride has a low affinity for nicotinic acetylcholine receptors (nAChR), thereby enhancing its selectivity for VMAT2. Synthetic structural changes of lobelane hydrochloride have led to some related analogs that show mild changes in affinity for VMAT2. The most potent synthetic lobelane hydrochloride obtained after structural modification has a K(i) value of 630 nM, showing significant VMAT2 selectivity. The biological activity of lobelane hydrochloride suggests that it has the potential to be used in the development of compounds to inhibit methamphetamine abuse .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
