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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2414 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2414)
2414 Results for "decrease" in MCE Product Catalog:
Cat. No.: HY-A0069AS
CAS No.: 1173020-59-1
Research Areas:
Succinylsulfathiazole (Standard) (Succinylsulphathiazole) is the analytical standard of Succinylsulfathiazole (HY-B0921). This product is intended for research and analytical applications. Succinylsulfathiazole is a long-acting sulfonamide antibiotic with localized gut-specific antibacterial activity and is orally active. Succinylsulfathiazole inhibits bacterial folate synthesis, reduces coliform counts, suppresses intestinal bacterial growth and vitamin biosynthesis, and depletes gut folate-producing bacteria. Succinylsulfathiazole modulates hepatic mTOR signaling, diminishes cecal fermentation, decreases hepatic folate levels and total folate excretion, elevates nitrogen excretion and reduces the fermentability of certain dietary fibers. Succinylsulfathiazole induces folate deficiency and triggers biotin- and folate-related nutritional deficiency symptoms in rats and C57BL/6 mice .
Cat. No.: HY-B1114R
CAS No.: 33342-05-1
Synonyms: AR-DF 26 (Standard)
Research Areas:
Gliquidone (Standard) is the analytical standard of Gliquidone. This product is intended for research and analytical applications. Gliquidone can bind to the pancreatic β-cells and increases insulin release to regulate blood glucose levels. Gliquidone significantly decreases LPS (HY-D1056)-induced proinflammatory responses and inhibits ERK/STAT3/NF-κB phosphorylation in BV2 microglial cells. Gliquidone can suppress microgliosis, microglial hypertrophy mediated by LPS, and proinflammatory cytokine COX-2 and IL-6 levels in murine model. Gliquidone also exhibits good anticancer activity in lung carcinoma cells. Gliquidone has antioxidant property. Gliquidone can be studied in research for type 2 diabetes and cancers .
Cat. No.: HY-D3404
CAS No.: 169454-13-1
Synonyms: Chuanxiongzine (Standard); Tetramethylpyrazine (Standard)
Cat. No.: HY-N0695R
CAS No.: 58546-55-7
Synonyms: Gomisin-B (Standard); Wuweizi ester-B (Standard); Schisantherin-B (Standard)
Cat. No.: HY-N11875S
Cat. No.: HY-N2492
CAS No.: 19367-38-5
Synonyms: Methyl trans-p-coumarate
Category:
Infection Plant Monophenols Other Phenylpropanoids Phenols Morinda citrifolia Linn. Extract Phenylpropanoids Disease Research Fields Rubiaceae Extract
Target:
Cat. No.: HY-N3741
CAS No.: 18296-45-2
Synonyms: Didrovaltratum
Cat. No.: HY-N6799
CAS No.: 36519-25-2
Target:
Pyruvate Kinase COX STAT TNF Receptor NO Synthase Interleukin Related HIF/HIF Prolyl-Hydroxylase
Research Areas:
Iminostilbene is a chemical precursor of carbamazepine. Additionally, Iminostilbene is an orally active inhibitor of PKM2 (Pyruvate Kinase M2) and COX2 (Cyclooxygenase-2). Iminostilbene exerts its effects by inhibiting PKM2 and its interaction with HIF-1α and STAT3, reducing COX2 and iNOS expression, and decreasing LPS-induced release of IL-1β, IL-6, TNF-α, and MCP-1, thereby suppressing macrophage-mediated inflammatory responses and improving myocardial ischemia/reperfusion (MI/R) injury. Iminostilbene holds promise for research in inflammation regulation, cardiovascular diseases (such as MI/R injury), and macrophage-mediated immune-related diseases .
Cat. No.: HY-N8376
CAS No.: 20725-03-5
Synonyms: (±)-Fustin; 3,7,3',4'-Tetrahydroxyflavanone
Category:
Flavanonols Plant Flavonoids Anacardiaceae Extract Toxicodendron vernicifluum (Stokes) F. A. Barkl. Extract Phenols Polyphenols
Target:
Cat. No.: HY-N8671
CAS No.: 256520-90-8
Cat. No.: HY-N9484S
CAS No.: 3028870-62-1
Cat. No.: HY-NP0204
Synonyms: Mouse Serum Albumin
Cat. No.: HY-P0037
CAS No.: 136208-71-4
Synonyms: Org 30850ANT
Target:
Research Areas:
Cat. No.: HY-P10462
CAS No.: 1403753-45-6
Synonyms: Synthetic anti-inflammatory peptide 15
Research Areas:
Cat. No.: HY-P10462A
Synonyms: Synthetic anti-inflammatory peptide 15 acetate
Research Areas:
Cat. No.: HY-P11291
Target:
Research Areas:
NNC0165-1273 is a selective NPY Y2 receptor agonist with a Ki of 2 nM and an EC50 of 5.0 nM. NNC0165-1273 blocks Ghrelin-induced cFos expression. NNC0165-1273 reduces nocturnal food intake, attenuates feeding behavior, induces early satiety, and causes dose-dependent decreases in body weight and fat mass in diet-induced obese mice. When used in combination with Semaglutide (HY-114118), NNC0165-1273 reduces preference for high-fat diet, promotes body weight loss, and produces sustained weight loss effects in diet-induced obese rats. NNC0165-1273 can be used in studies related to diet-induced obesity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
