83 Results for "

CD 38

" in MedChemExpress (MCE) Product Catalog:
Products (83)

83 Results for "CD 38" in MCE Product Catalog:

Cat. No.: HY-P990037
CAS No.: 2430792-01-9
Synonyms: GEN3014

Target:  

CD38

Research Areas:  

Inflammation/Immunology Cancer

Erzotabart is an IgG1-kappa, anti-CD38 (ADP-ribosyl cyclase 1, cyclic ADP-ribose hydrolase 1, cADPr hydrolase 1, cADPR1) Homo sapiens monoclonal antibody. Erzotabart shows antineoplastic activity .
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Cat. No.: HY-P10563
CAS No.: 2580150-96-3
Synonyms: BHV-1100
Target:  

CD38 IFNAR

Research Areas:  

Cancer

Noraramtide (BHV-1100) is an antibody-recruiting molecule. Noraramtide binds to CD38 and recruits natural killer (NK) cells to mediate antibody-dependent cellular cytotoxicity. Noraramtide enhances the capacity of autologous cytokine-induced memory-like (CIML) NK cells to produce IFNγ and CD107a, thereby improving their cytotoxicity against multiple myeloma cells. Noraramtide can be used in the research of multiple myeloma .
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Cat. No.: HY-N8189
CAS No.: 119425-91-1
Loureirin D is a selective P2Y12 receptor antagonist that penetrates the blood-brain barrier. Loureirin D inhibits the MAPK/JNK/ERK/p38 signaling pathway in microglia by acting on CD38, and inhibits ADP (HY-W010918)-induced platelet aggregation, MMP2/9-mediated tight junction disruption, and ischemia-related blood-brain barrier damage. Loureirin D protects endothelial cells from OGD-induced apoptosis. Loureirin D is used in studies of ischemic stroke and thrombosis .
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Cat. No.: HY-134358
CAS No.: 133575-27-6
Target:  

CD38

Research Areas:  

Neurological Disease

Ara-F-NAD+ is an arabino analogue of NAD +. Ara-F-NAD+ is a potent, reversible and slow-binding CD38 NADase inhibitor .
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Cat. No.: HY-120255
CAS No.: 155976-53-7
Synonyms: 17(R)-HDoHE
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells .
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Cat. No.: HY-RS02239
Research Areas:  

Others

CD38 Human Pre-designed siRNA Set A contains three designed siRNAs for CD38 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS02241
Research Areas:  

Others

Cd38 Rat Pre-designed siRNA Set A contains three designed siRNAs for Cd38 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-119648A
CAS No.: 301687-87-6
Purity:  98.00%
Target:  

CD38

Research Areas:  

Inflammation/Immunology

(E/Z)-CCR-11 (Comp 12) is a selective CD38 inhibitor, with an IC50 of 20.8 μM against CD38 cyclase. (E/Z)-CCR-11 promotes increases in cellular NAD+ levels and interferon γ .
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Cat. No.: HY-171417
CAS No.: 1119281-04-7
Target:  

CD38

Research Areas:  

Cancer

6-Alkyne-F-araNAD is an irreversible inhibitor of CD38. 6-Alkyne-F-araNAD helps other fluorescent probes (such as SR101−F-araNMN) to more clearly observe the localization of intracellular CD38 .
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Cat. No.: HY-P991461
Synonyms: XmAb968

Target:  

CD38

Research Areas:  

Cancer

AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 & CD3E. AMG-424 kills CD38-expressing cancer cells, triggers T-cell proliferation and attenuates cytokine release. AMG 424 has antitumor activity in a bone marrow-invasive mouse cancer model and induces peripheral B-cell depletion in cynomolgus monkeys. AMG-424 can be used in multiple myeloma research. Recommended isotype control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3 .
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Cat. No.: HY-N0640R
CAS No.: 7084-24-4
Synonyms: Chrysontemin (Standard); Cyanidin 3-O-glucoside chloride (Standard)
Kuromanin (chloride) (Standard) is the analytical standard of Kuromanin (chloride). This product is intended for research and analytical applications. Kuromanin chloride (Chrysontemin) is derived from mulberry leaves and has the effect of increasing blood sugar concentration and maintaining lipid metabolism balance to reduce obesity. Kuromanin chloride can inhibit CD38 enzymatic activities .
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Cat. No.: HY-123999R
CAS No.: 1700637-55-3
Research Areas:  

Metabolic Disease

CD38 inhibitor 1 (Standard) is the analytical standard of CD38 inhibitor 1 (HY-123999). This product is intended for research and analytical applications. CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38 .
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Cat. No.: HY-164628
CAS No.: 314039-40-2
Target:  

CD38

Research Areas:  

Cancer

CD38-IN-5 (compound 1) is a CD38 inhibitor that selectively inhibits CD38 hydrolase with an IC50 of 4.0 μM. CD38-IN-5 does not inhibits CD38 cyclase. CD38-IN-5 is highly effective at promoting NK cell-mediated tumor toxicity. CD38-IN-5 increases NADH+ and IFNγ levels in activated PBMCs. CD38-IN-5 can be used for the study of cancer .
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Cat. No.: HY-156789
CAS No.: 524055-93-4
Target:  

CD38

Research Areas:  

Neurological Disease Cancer

CD38-IN-4 is a CD38 inhibitor. CD38-IN-4 inhibits CD38 hydrolase enzymatic activity through mixed inhibition kinetics, binding partially inside and partially outside the NAD + catalytic pocket. CD38-IN-4 acts as a DNA-binding agent . CD38-IN-4 can be used for research on neuroblastoma .
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Cat. No.: HY-101780A
CAS No.: 1793059-58-1
Synonyms: EDO-S101 hydrochloride; NL-101 hydrochloride
Target:  

HDAC

Research Areas:  

Cancer

Tinostamustine hydrochloride (EDO-S101 hydrochloride) is a compound with anti-multiple myeloma activity and the ability to promote CD38 expression. Tinostamustine hydrochloride enhances the sensitivity of tumor cells to the anti-CD38 monoclonal antibody daratumumab by increasing the acetylation level of histone H3. Tinostamustine hydrochloride can increase the expression of MICA and MICB, thereby activating NK cells. Tinostamustine hydrochloride can significantly delay tumor growth and improve the survival rate of mice .
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Cat. No.: HY-186178
CAS No.: 2766686-04-6
Target:  

CD38

CD38-IN-6 is an orally active CD38 inhibitor. CD38-IN-6 regulates NAD + metabolite levels in the liver of aged obese mice by increasing NAD + and NMN levels, and decreasing NAM and ADPR levels. CD38-IN-6 alleviates inflammatory responses in mice. CD38-IN-6 can be used for research related to obesity and inflammation .
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Cat. No.: HY-184493
CAS No.: 2597933-37-2
Target:  

CD38

Research Areas:  

Cancer

CD38-IN-7 is a CD38 inhibitor with an IC50 of less than 0.01 μM against hCD38. CD38-IN-7 can be used for research on various cancers .
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Cat. No.: HY-P991715
CAS No.: 3028478-15-8
Synonyms: SG-301

Target:  

CD38

Research Areas:  

Inflammation/Immunology

Sanritatug (SG-301) is an anti-CD38 IgG1κ antibody with potential antineoplastic activity. The corresponding isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991462

Target:  

CD38

Research Areas:  

Cancer

GBR-1342 is a human bispecific antibody (bsAb) targeting CD38 & CD3. GBR-1342 inhibits the activity of Daudi, RAJI, RPMI8226, IM-9, and NCI-H929 cancer cell lines. GBR-1342 can be used in myeloma research .
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Cat. No.: HY-P86482
Synonyms: CD38; ADP-ribosyl cyclase 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD antigen CD38

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Mouse, Rat

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