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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
75 Results for "
HSV-2
" in MedChemExpress (MCE) Product Catalog:
Products (75)
75 Results for "HSV-2" in MCE Product Catalog:
Cat. No.: HY-A0181S1
Cat. No.: HY-P2310A
Target:
Bacterial Parasite Apoptosis HIV HSV CMV TNF Receptor Interleukin Related NOD-like Receptor (NLR) DNA/RNA Synthesis Influenza Virus
Research Areas:
Cat. No.: HY-17422R
CAS No.: 59277-89-3
Synonyms: Aciclovir (Standard); Acycloguanosine (Standard)
Acyclovir (Standard) is the analytical standard of Acyclovir. This product is intended for research and analytical applications. Acyclovir (Aciclovir) is a potent, orally active antiviral agent. Acyclovir has antiherpetic activity with IC50 values of 0.85 μM and 0.86 μM for HSV-1 and HSV-2, respectively. Acyclovir induces cell cycle perturbation and apoptosis. Acyclovir prevents bacterial infections during induction therapy for acute leukaemia [2] .
Cat. No.: HY-18944
CAS No.: 1113044-49-7
Target:
Research Areas:
FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.
Cat. No.: HY-17422S1
CAS No.: 1185179-33-2
Synonyms: Aciclovir-d4; Acycloguanosine-d4
Cat. No.: HY-N12717
CAS No.: 79786-01-9
Cat. No.: HY-50735
CAS No.: 69123-90-6
Synonyms: NSC 382097; FIAC; FOAC
Target:
Research Areas:
Fiacitabine (NSC 382097; FIAC; FOAC) is a potent and highly selective anti-herpesvirus agent. Fiacitabine acts as an inhibitor of HSV DNA polymerase, with a Ki of 0.26 μM for HSV-1 and 0.42 μM for HSV-2, respectively. Fiacitabine can be efficiently phosphorylated by thymidine kinase encoded by the virus itself to generate FIACTP, an active triphosphate metabolite. Fiacitabine is applicable to research related to herpesvirus infections [2].
Cat. No.: HY-A0181S3
Synonyms: AMP-13C10 dilithium
Cat. No.: HY-131606
CAS No.: 142276-31-1
Target:
Research Areas:
Cidofovir diphosphate is an active intracellular metabolite of Cidofovir. Cidofovir diphosphate is a selective inhibitor of viral DNA polymerases with Ki values of 6.6, 0.86 and 1.4 μM for HCMV, HSV-1 and HSV-2 DNA polymerase, respectively [2].
Cat. No.: HY-17424R
CAS No.: 39809-25-1
Synonyms: BRL 39123 (Standard); VSA 671 (Standard)
Target:
Research Areas:
Penciclovir (Standard) is the analytical standard of Penciclovir. This product is intended for research and analytical applications. Penciclovir (VSA 671) is a potent and selective anti-herpesvirus agent with EC50 values of 0.5, 0.8 µg/ml for HSV-1 (HFEM), HSV-2 (MS), respectively. Penciclovir shows anti-herpesvirus activity with no-toxic. Penciclovir preventes mortality in mouse [2].
Cat. No.: HY-A0181S2
Synonyms: AMP-d12 dilithium
Synonyms: SCV 07 hydrochloride; Gamma-D-glutamyl-L-tryptophan hydrochloride
Research Areas:
Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and splenic cell proliferation, and improves macrophage function. Golotimod hydrochloride (SCV 07 hydrochloride) inhibits STAT3 signaling and modulates the duration and severity of oral mucositis in animal models that received radiation or a combination of radiation and Cisplatin. Golotimod hydrochloride (SCV 07 hydrochloride) is also a potential therapeutic for recurrent genital herpes simplex virus type 2 (HSV-2) [2] .
Cat. No.: HY-P3795
CAS No.: 361443-81-4
Target:
Research Areas:
Cat. No.: HY-170547
CAS No.: 2701561-91-1
Target:
Research Areas:
DNA polymerase-IN-6 is an antiviral agent and a DNA polymerase inhibitor. DNA polymerase-IN-6 inhibits the replication of HCMV, HSV-1, HSV-2 and EBV. DNA polymerase-IN-6 exhibits low cytotoxicity in mammalian cells. DNA polymerase-IN-6 can be used in research related to viral infections .
Cat. No.: HY-149022
CAS No.: 2490468-31-8
Target:
Research Areas:
HSV-1/HSV-2-IN-1 (compound 7d) is a HSV-1 and HSV-2 inhibitor, with EC50s of 7.6, 7.6, 4, and 12 μM for HSV-1 (KOS), HSV-2 (G), HSV-1 TK - KOS ACV r and vaccinia virus in human embryonic lung fibroblast cell cultures .
Synonyms: SCV 07; Gamma-D-glutamyl-L-tryptophan
Research Areas:
Cat. No.: HY-A0181S6
Synonyms: AMP-13C10,15N5
Cat. No.: HY-149023
CAS No.: 2490468-39-6
HSV-1/HSV-2-IN-2 is a HSV-1, HSV-2 and VV inhibitor with EC50 values of 6.8, 8.9 and 8.9 µM, respectively. HSV-1/HSV-2-IN-2 shows antiviral activity .
Cat. No.: HY-A0181S4
Synonyms: AMP-13C10,15N5,d12 dilithium
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
