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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
249 Results for "
ROS generation
" in MedChemExpress (MCE) Product Catalog:
Products (249)
249 Results for "ROS generation" in MCE Product Catalog:
5
5
5 Cited Publications
Cat. No.: HY-N1472
CAS No.: 88182-33-6
4
4 Cited Publications
Synonyms: Cichoric acid; Dicaffeoyltartaric acid
4
4 Cited Publications
Target:
Research Areas:
CORM-3, a carbon monoxide-releasing molecule, attenuates NF-κB p65 nuclear translocation, reduces ROS generation and enhances intracellular glutathione and superoxide dismutase levels. CORM-3 reduces NLRP3 inflammasome activation .
4
4 Cited Publications
4
4 Cited Publications
Research Areas:
GSK5182 is a highly selective and orally active inverse agonist of estrogen-related receptor γ (ERRγ) with an IC50 of 79 nM. GSK5182 does not interact with other nuclear receptors, including ERRα or ERα. GSK5182 also induces reactive oxyen species (ROS) generation in hepatocellular carcinoma (HCC) .
4
4 Cited Publications
Synonyms: CSG-452 hydrate
Target:
Research Areas:
Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific sodium/glucose cotransporter 2 (SGLT2) inhibitor with an IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2 . Tofogliflozin partially inhibits high glucose-induced reactive oxyen species (ROS) generation in tubular cells .
4
4 Cited Publications
Cat. No.: HY-N0805
CAS No.: 26575-95-1
Synonyms: 23-Acetylalismol B; 23-O-Acetylalisol B; Alisol B monoacetate
3
3 Cited Publications
Synonyms: DS-6051b; AB-106; IBI-344
Target:
Research Areas:
Taletrectinib (DS-6051b) is a potent, orally active, and next-generation selective ROS1/NTRK inhibitor. Taletrectinib potently inhibits recombinant ROS1, NTRK1, NTRK2, and NTRK3 with IC50s of 0.207, 0.622, 2.28, and 0.98 nM, respectively. Taletrectinib also inhibits ROS1 G2032R and other Crizotinib-resistant ROS1 mutants .
3
3 Cited Publications
Synonyms: Creatine phosphate; Creatinephosphoric acid
3
3
3 Cited Publications
Cat. No.: HY-D0885D
CAS No.: 19333-65-4
3
3 Cited Publications
Cat. No.: HY-N6893
CAS No.: 54999-07-4
2
2
Research Areas:
Lexibulin (CYT-997) is a potent and orally active tubulin polymerisation inhibitor with IC50s of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo . Lexibulin induces cell apoptosis and induces mitochondrial ROS generation in GC cells .
2
2
2 Cited Publications
Synonyms: L-Ascorbate (Standard); Vitamin C (Standard)
2
Category:
Triterpenes Terpenoids Other Diseases Amaranthaceae Plants Alternanthera philoxeroides (Mart.) Griseb. Disease Research Fields
Target:
2
2
2 Cited Publications
Cat. No.: HY-N6865
CAS No.: 38691-95-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
