2086 Results for "

hydroxy

" in MedChemExpress (MCE) Product Catalog:
Products (2086)

2086 Results for "hydroxy" in MCE Product Catalog:

7
7 Cited Publications
Art. -Nr.: HY-B1739
CAS. Nr.: 1247-64-9
Synonyms: 3β-hydroxy-5-pregnen-20-one monosulfate
Pregnenolone monosulfate (3β-Hydroxy-5-pregnen-20-one monosulfate) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones. Pregnenolone monosulfate acts as a signaling-specific inhibitor of cannabinoid CB1 receptor, inhibits the effects of tetrahydrocannabinol (THC) that are mediated by the CB1 receptors. Pregnenolone monosulfate can protect the brain from cannabis intoxication . Pregnenolone monosulfate is also a TRPM3 channel activator, and also can weakly activate TRPM1 channels .
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7
7 Cited Publications
Art. -Nr.: HY-112885A
CAS. Nr.: 1140844-63-8
Reinheit:  98.81%
Synonyms: Nω-hydroxy-nor-L-arginine acetate
nor-NOHA acetate is a selective and reversible Arginase inhibitor. nor-NOHA acetate induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA acetate has anti-leukemic activity. nor-NOHA acetate improves liver ischemia-reperfusion injury. nor-NOHA acetate can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
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7
7 Cited Publications
Art. -Nr.: HY-112885C
CAS. Nr.: 291758-32-2
Reinheit:  98.85%
Synonyms: Nω-hydroxy-nor-L-arginine dihydrochloride
nor-NOHA dihydrochloride is a selective and reversible Arginase inhibitor. nor-NOHA dihydrochloride induces Apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA dihydrochloride has anti-leukemic activity. nor-NOHA dihydrochloride improves liver ischemia-reperfusion injury. nor-NOHA dihydrochloride can used in study of tuberculosis, endothelial dysfunction, immunosuppression and metabolism .
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7
7 Cited Publications
Art. -Nr.: HY-100793
CAS. Nr.: 126411-39-0
Reinheit:  99.80%
Synonyms: GW 485801
SR12813 (GW 485801) is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase, with an IC50 value of 0.85 μM . SR12813 is also an efficient agonist of human pregnane X receptor (hPXR). SR12813 can strongly bind to hPXR but not to mouse PXR (mPXR) .
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7
7 Cited Publications
Art. -Nr.: HY-112885B
CAS. Nr.: 2250019-93-1
Reinheit:  99.96%
Synonyms: Nω-hydroxy-nor-L-arginine monoacetate
nor-NOHA monoacetate is a selective and reversible arginase inhibitor. nor-NOHA monoacetate induces apoptosis in ARG2-expressing cells under hypoxia. nor-NOHA monoacetate has anti-leukemic activity. nor-NOHA monoacetate can used in study of endothelial dysfunction, immunosuppression and metabolism .
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7
7 Cited Publications
Art. -Nr.: HY-N0098
CAS. Nr.: 121-33-5
Synonyms: p-Vanillin; m-Methoxy-p-hydroxybenzaldehyde; p-hydroxy-m-methoxybenzaldehyde
Vanillin (p-Vanillin) is a single molecule extracted from vanilla beans and also a popular odor used widely in perfume, food and medicine.
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6
6 Cited Publications
Art. -Nr.: HY-100653A
CAS. Nr.: 1869912-40-2
Reinheit:  99.80%
Forschungsgebiete:  

Cancer

AZD5153 6-Hydroxy-2-naphthoic acid is the 6-Hydroxy-2-naphthoic acid of AZD5153. AZD5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor; disrupts BRD4 with an IC50 of 1.7 nM.
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6
6 Cited Publications
Art. -Nr.: HY-17461
CAS. Nr.: 53-06-5
Synonyms: 17-hydroxy-11-dehydrocorticosterone; Kendall's compound E
Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations .
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6
6 Cited Publications
Art. -Nr.: HY-N7378
CAS. Nr.: 115819-92-6
Synonyms: 1-hydroxy-2-piperidinecarboxylic acid; NHP
N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxypipecolic acid accumulates systemically in the plant foliage in response to pathogen attack. N-Hydroxypipecolic acid induces SAR to bacterial and oomycete infection .
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6
6 Cited Publications
Art. -Nr.: HY-N1363
CAS. Nr.: 14113-05-4
Synonyms: (E)-Queen Bee Acid; (E)-10-hydroxy-2-decenoic acid
Royal Jelly Acid ((E)-Queen Bee Acid) is a major fatty acid found in royal jelly with oral bioavailability, exhibiting anti-inflammatory, anticancer, antimalarial, antiprotozoal, and neuroregulatory activities. Royal Jelly Acid can be used for research in various fields, including cancer, infections, immune inflammation, and neurological diseases .
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4
4 Cited Publications
Art. -Nr.: HY-N6949
CAS. Nr.: 481-39-0
Synonyms: 5-hydroxy-1,4-naphthalenedione
Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity .
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4
4 Cited Publications
Art. -Nr.: HY-B1159
CAS. Nr.: 4008-48-4
Synonyms: 8-hydroxy-5-nitroquinoline; 5-Nitro-8-quinolinol
Forschungsgebiete:  

Infection Cancer

Nitroxoline (8-Hydroxy-5-nitroquinoline), an antibiotic, is an orally active antibiofilm agent. Nitroxoline reduces the formation and induces the dispersal of Pseudomonas aeruginosa biofilms by chelation of iron and zinc. Nitroxoline can be used for the urinary tract infections and cancer research .
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4
4 Cited Publications
Art. -Nr.: HY-132589
CAS. Nr.: 1867157-35-4
Synonyms: ALN-TTRsc02
Vutrisiran (ALN-TTRsc02) is a liver-directed, investigational, small interfering ribonucleic acid (siRNA) agent. Vutrisiran can be used for transthyretin (TTR)-mediated amyloidosis research .
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4
4 Cited Publications
Art. -Nr.: HY-128374
CAS. Nr.: 3671-99-6
Reinheit:  99.93%
D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6 .
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3
3 Cited Publications
Art. -Nr.: HY-N6825
CAS. Nr.: 83883-10-7
Hydroxy-α-sanshool is a transient receptor potential ankyrin 1 (TRPA1) and TRP vanilloid 1 (TRPV1) agonist with EC50s of 69 and 1.1 μM, respectively. Hydroxy-α-sanshool can be used for pain research .
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3
3 Cited Publications
Art. -Nr.: HY-N0761
CAS. Nr.: 537-73-5
Synonyms: 3-hydroxy-4-methoxycinnamic acid
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes .
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3
3 Cited Publications
Art. -Nr.: HY-B0172A
CAS. Nr.: 2276-93-9
Synonyms: 3β-hydroxy-5α-cholanic acid
Target:  

Drug Derivative

Forschungsgebiete:  

Inflammation/Immunology

Isoallolithocholic acid (3β-Hydroxy-5α-cholanic acid), a derivative of Lithocholic acid (HY-10219), is a T cell regulator. Isoallolithocholic acid enhances regulatory T cells (Tregs) differentiation .
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3
3 Cited Publications
Art. -Nr.: HY-119222
CAS. Nr.: 862892-90-8
Reinheit:  99.11%
Target:  

GPR109A

Forschungsgebiete:  

Metabolic Disease

GSK256073 is a potent, selective and orally active GPR109A agonist and a long-lasting and non-flushing HCA2 full agonist with a pEC50 of 7.5 (human HCA2). GSK256073 acutely improves glucose homeostasis via inhibition of lipolysis and has the potential for the study of type 2 diabetes mellitus (T2DM)and dyslipidemia . GPR109A: G-protein coupled receptor 109A; HCA2: hydroxy-carboxylic acid receptor 2
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2
2 Cited Publications
Art. -Nr.: HY-W008437
CAS. Nr.: 18835-59-1
(S)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid dihydrate is an endogenous metabolite.
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2
2 Cited Publications
Art. -Nr.: HY-113294
CAS. Nr.: 484-78-6
Reinheit:  99.90%
Synonyms: 3-hydroxy-DL-kynurenine
3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis .
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