311 Results for "

neutral

" in MedChemExpress (MCE) Product Catalog:
Products (311)

311 Results for "neutral" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-D1237
CAS No.: 21658-70-8
BODIPY505/515 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 505/515 nm .
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2
2 Cited Publications
Cat. No.: HY-B1274
CAS No.: 58473-74-8
Synonyms: trans-3-Bromo-N-ethylcinnamamide
Cinromide is an anticonvulsant agent. Cinromide inhibits epithelial neutral amino acid transporter B 0AT1 (SLC6A19) with an IC50 of 0.5 μM .
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2
2 Cited Publications
Cat. No.: HY-13662B
CAS No.: 138530-94-6
Purity:  98.91%
Synonyms: Dexlansoprazole
Target:  

Exosomes Proton Pump

Research Areas:  

Inflammation/Immunology Cancer

(R)-Lansoprazole is the R enantiomer of Lansoprazole, Lansoprazole (AG 1749) is an orally active proton pump inhibitor which prevents the stomach from producing acid. Lansoprazole (AG 1749) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor (exosome inhibitor) .
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2
2 Cited Publications
Cat. No.: HY-W011404
CAS No.: 60-01-5
Synonyms: Glyceryl tributyrate
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed proagent of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracellular lipases, releasing effective butyrate directly into the cell in vivo. Tributyrin has potent antiproliferative, proapoptotic and differentiation-inducing effects .
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2
2 Cited Publications
Cat. No.: HY-D1224
CAS No.: 99792-79-7
Synonyms: CPRG
Chlorophenol red-β-D-galactopyranoside (CPRG) is an efficient and sensitive chromogenic substrate for β-galactosidase (HY-P2869), widely used in colorimetric assays. Chlorophenol red-β-D-galactopyranoside itself appears pale yellow. When it is specifically hydrolyzed by β-galactosidase, it releases chlorophenol red. The released chlorophenol red turns purple-red under alkaline or neutral pH conditions. This color change from yellow to red can be quantitatively detected at wavelengths of 540-572 nm using visible spectrophotometry .
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2
2 Cited Publications
Cat. No.: HY-D1617
CAS No.: 144672-74-2
BODIPY 500/510 C1, C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 500/510 nm . Protect from light, stored at -20°C.
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1
1 Cited Publications
Cat. No.: HY-D0213
CAS No.: 4197-25-5
Research Areas:  

Others

Sudan Black B, a fat-soluble diazo dye, is a histochemical stain. Sudan Black B can be used for staining of neutral triglycerides and lipids .
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1
1 Cited Publications
Cat. No.: HY-131002
CAS No.: 351353-48-5
Purity:  99.68%
Target:  

Exosomes Phospholipase

Research Areas:  

Inflammation/Immunology

DPTIP is a potent brain penetrant neutral sphingomyelinase 2 (N-SMase 2) inhibitor (exosome inhibitor), with an IC50 of 30 nM .
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1
1 Cited Publications
Cat. No.: HY-W019883
CAS No.: 7758-11-4
Dipotassium hydrogen phosphate is a salt. Dipotassium hydrogen phosphate can enhance the lipase production of Rhizopous oligosporous in neutral pH phosphate buffer. Dipotassium hydrogen phosphate can be used as a pharmaceutical excipient, such as a pH adjuster, a buffer .
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1
1 Cited Publications
Cat. No.: HY-N2339
CAS No.: 61510-09-6
Synonyms: Cholesteryl docosanoate; Cholesterol behenate
Cholesteryl behenate is a cholesterol ester associated with the neutral core of low density lipoprotein Receptor-LDL complexes are taken up by lysosomes and hydrolyzed to release cholesterol from the esters.
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1
1 Cited Publications
Cat. No.: HY-121827
CAS No.: 611207-11-5
Purity:  99.83%
Target:  

Cannabinoid Receptor

Research Areas:  

Metabolic Disease

LH-21 is a potent in vivo neutral cannabinoid CB1 receptor antagonist. LH-21 reduces food intake and body weight gain in obese Zucker rats. , and displays efficacy as a feeding inhibitor .
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1
1 Cited Publications
Cat. No.: HY-P76735
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ASAH2; BCDase; N-Acylsphingosine Amidohydrolase 2; LCDase; neutral Ceramidase; NCDase; Non-Lysosomal Ceramidase; HNAC1; N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2; neutral/Alkaline Ceramidase; Acylsphingosine Deacylase 2; Mitochondrial
Species:  
Mouse
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-118643
CAS No.: 1620330-72-4
Purity:  99.82%
Synonyms: BMS-986231; CXL-1427
Target:  

Drug Intermediate

Research Areas:  

Cardiovascular Disease

Cimlanod (BMS-986231) is a second-generation Nitroxyl (HNO) donor for heart failure. Cimlanod (BMS-986231) delivers HNO via pH-dependent chemical breakdown when exposed to the neutral pH environment of the bloodstream. Cimlanod (BMS-986231) possesses positive lusitropic and inotropic as well as vasodilatory effects. Cimlanod is the prodrug of CXL-1020 (HY-147384) .
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1
1 Cited Publications
Cat. No.: HY-Y0756
CAS No.: 144-55-8
Synonyms: Sodium hydrogen carbonate
Target:  

Bacterial

Research Areas:  

Infection Cancer

Sodium bicarbonate (Sodium hydrogen carbonate; Soda bicarbonate) is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .
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1
1 Cited Publications
Cat. No.: HY-142021
CAS No.: 156192-32-4
Purity:  99.24%
Target:  

Cathepsin Parasite

Research Areas:  

Infection Inflammation/Immunology

Z-Leu-Arg-AMC is a fluorogenic peptide substrate for cysteine proteases (e.g., Cathepsin) (Ex=350 nm,Em=460 nm). Z-Leu-Arg-AMC is preferentially cleaved by Cathepsin K and S under weakly acidic conditions, while its hydrolysis relies on residual Cathepsin S activity at neutral pH. Z-Leu-Arg-AMC serves as a substrate for recombinant Sphenophorus levis Cathepsin L, falcipain-2, falcipain-3, berghepain-2, knowlepain-2, vivapain-2, as well as falcipain-2 chimeras and constructs. It enables quantitative detection of cysteine protease activity in human inflammatory bronchoalveolar lavage fluid via fluorescence generation. Z-Leu-Arg-AMC can be used in research related to pulmonary inflammatory diseases and malaria .
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Cat. No.: HY-Y0873C
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 3350
PEG3350 (Polyethylene glycol 3350) a neutral polymer of molecular weight 3350. PEG3350 used as an excellent solvent for a large number of substances.
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Cat. No.: HY-Y0873K
CAS No.: 25322-68-3
Synonyms: Polyethylene glycol 200
PEG200 (Polyethylene glycol 200), a neutral polymer of molecular weight 200, is a water-soluble, low immunogenic and biocompatible polymer formed by repeating units of ethylene glycol .
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Cat. No.: HY-D0166
CAS No.: 553-24-2
Target:  

Fluorescent Dye

Research Areas:  

Others

Neutral Red is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant.
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Cat. No.: HY-131577A
CAS No.: 42613-33-2
Synonyms: Dispase I
Target:  

Collagen

Research Areas:  

Others

Neutral protease I (Dispase I) is a rapid, effective, gentle and neutral protease that can separate intact epidermis from the dermis. Neutral protease I can also separate intact epithelial sheets in culture from the substratum. Neutral protease I preserves the viability of the epithelial cells while cleaving the basement membrane zone region. Neutral protease I can also be used to prevent clumping in suspension cultures. Neutral protease I cleaves fibronectin and type IV collagen, but not laminin, type V collagen, serum albumin, or transferrin .
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Cat. No.: HY-D0166A
CAS No.: 553-24-2
Research Areas:  

Others

Neutral Red (IND) is an organic dye commonly used in biology and cytology laboratories. It can be used to stain living cells, secreted proteins and other molecular structures, etc., and has a wide range of applications in cell imaging and staining. In addition, Neutral Red (IND) is widely used in industrial fields such as water treatment, food processing and paper manufacturing, for example as an indicator or colorant.
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