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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
95 Results for "
A2b
" in MedChemExpress (MCE) Product Catalog:
Products (95)
95 Results for "A2b" in MCE Product Catalog:
Cat. No.: HY-W587488
CAS No.: 84-21-9
Synonyms: 3′-AMP
Research Areas:
Adenosine 3’-monophosphate (3’-AMP) is a nucleotide. Adenosine 3’-monophosphate is a cyclic AMP production agonist. Adenosine 3’-monophosphate increases cyclic AMP levels concentration-dependently in NG108-15 cells. Adenosine 3’-monophosphate can be used in the determination of acid phosphatase activity of human serum, which is estabilished as a laboratory procedure in the diagnosis of prostate cancer, metastatic mammary cancer and Gaucher’s disease. Adenosine 3’-monophosphate inhibits human aortic and coronary vascular smooth muscle cell proliferation via A2B receptors [2] .
Research Areas:
Enprofylline acts as a selective and competitive A2B receptor antagonist with the Ki of 7 μM. Enprofylline also acts as a phosphodiesterase inhibitor. Enprofylline can be used for the research of asthma, chronic obstructive pulmonary disease [2] .
Target:
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Alloxazine is a selective A2b antagonist. Alloxazine completely block 5’N-Ethylcarboxamido adenosine (NECA)-mediated cyclic AMP accumulation with an IC50 of 2.9 μM. Alloxazine can be used for the research of cancer [2].
Cat. No.: HY-B0228S6
CAS No.: 82741-17-1
Synonyms: Adenine riboside-d2; D-Adenosine-d2
Cat. No.: HY-B0228S4
CAS No.: 201996-55-6
Synonyms: Adenine riboside-1′-13C; D-Adenosine-1′-13C
Cat. No.: HY-B0228S
CAS No.: 109923-50-4
Synonyms: Adenine riboside-d1; D-Adenosine-d
Target:
Research Areas:
BAY-545 is a potent and selective A2B adenosine receptor antagonist, with an IC50 of 59 nM. BAY-545 also exhibits IC50s of 66, 400, 280 nM for human, mouse, rat A2B adenosine receptor in cells, respectively, and a Ki of 97 nM for human A2B adenosine receptor, with more selectivity over A1, A2A, and A3 adenosine receptor .
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ISAM-140 (22b) is a potent and highly selective A2B adenosine receptor antagonist with a Ki of 3.49 nM .
Target:
PSB-0788 is a new selective high-affinity A2B antagonist with IC50 value of 3.64 nM and Ki value of 0.393 nM, respeactively. PSB-0788 can be used for the research for chronic inflammatory lung diseases .
Cat. No.: HY-153897
CAS No.: 2332835-02-4
Target:
Research Areas:
PSB-1901 is a potent A2B adenosine receptor (A2BAR) antagonist with Kis of 0.0835 nM and 0.131 nM for human and mouse A2BARs respectively. PSB-1901 can be used for the research of cancer .
Cat. No.: HY-B0228S5
CAS No.: 54447-57-3
Synonyms: Adenine riboside-13C; D-Adenosine-13C
Target:
Research Areas:
LUF5834 is a selective A2B adenosine receptor (A2BR) partial agonist (EC50 = 12 nM). LUF5834 is also a partial A1/A2A adenosine receptor agonist (lacking selectivity) with Ki values of 2.6 and 28 nM, respectively [2].
Cat. No.: HY-U00321
CAS No.: 531506-36-2
Target:
Research Areas:
A2B receptor antagonist 1 is a potent A2B adenosine receptor antagonist extracted from patent WO 2009157938 A1 EXAMPLE 9B.
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Research Areas:
KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC50=445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC50s of 2390 nM and 2550 nM, respectively [2].
Cat. No.: HY-B0228S12
Synonyms: Adenine riboside-d13; D-Adenosine-d13
Cat. No.: HY-129092
CAS No.: 80206-91-3
Synonyms: 8-SPT; 8-pSPT
Target:
Research Areas:
8-(p-Sulfophenyl)theophylline (8-SPT) (compound 2) is an adenosine A2B receptor antagonist, with a Ki of 1330 nM for A2B human recombinant .
Cat. No.: HY-136897
CAS No.: 65195-54-2
Category:
Target:
Cat. No.: HY-111295
CAS No.: 851371-22-7
Target:
Research Areas:
LAS38096 is a potent, selective, and efficacious A2B Adenosine Receptor antagonist, with a Ki of 17 nM .
Cat. No.: HY-103182A
CAS No.: 409344-71-4
Target:
Research Areas:
PSB-1115 potassium salt is a selective A2B Adenosine Receptor antagonist. PSB-1115 potassium salt inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced contraction inhibition of acetylcholine (ACh) .
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Research Areas:
Adenosine receptor antagonist 2 is an orally active A2a/A2b adenosine receptor antagonist with IC50s of 1 nM and 3 nM, respectively. Adenosine receptor antagonist 2 has anti-tumor activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
