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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10357 Results for "
dimer-based compound
" in MedChemExpress (MCE) Product Catalog:
Products (10357)
10357 Results for "dimer-based compound" in MCE Product Catalog:
20
20 Cited Publications
Cat. No.: HY-W010968
CAS No.: 149022-20-8
Synonyms: A-5'-P sodium hydrate; AMP sodium hydrate; Adenosine 5'-monophosphate sodium hydrate
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19 Cited Publications
Synonyms: Rheic Acid; Rhubarb yellow; Monorhein
18
18 Cited Publications
Synonyms: γ-Secretase-IN-1
Target:
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Compound E is a γ-secretase inhibitor. Compound E blocks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
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18
18 Cited Publications
Cat. No.: HY-W015913
CAS No.: 113-24-6
Synonyms: Sodium 2-oxopropanoate; Acetylformic acid sodium
17
Category:
Plants Monophenols Ginkgoaceae Extract Simple Phenylpropanols Ketones, Aldehydes, Acids Phenols Ginkgo biloba L. Phenylpropanoids Disease Research Fields Cancer
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17
17 Cited Publications
Synonyms: 8-Methoxypsoralen; Xanthotoxin; 8-MOP
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17 Cited Publications
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Research Areas:
NF-κΒ activator 1 (compound 32) is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression .
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NG 52 is a potent, cell-permeable, selective, ATP-compatible and orally active Cdc28p and Pho85p kinase inhibitor with IC50s of 7 μM and 2 μM, respectively. NG 52 also inhibits the activity of phosphoglycerate kinase 1 (PGK1) with an IC50 of 2.5 μM. NG 52 is inactive against yeast kinases Kin28p, Srb10, and Cak1p .
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16 Cited Publications
Synonyms: (S)-(+)-[6]Gingerol
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16 Cited Publications
Research Areas:
p38 MAPK-IN-1 (Compound 4) is a novel potent and selective inhibitor of p38 MAPK with IC50 of 68 nM. p38 MAPK-IN-1 shows sustained levels, low clearance and good bioavailability.
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15 Cited Publications
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BMS-986299 (compound 112) is a first-in-class NLRP3 inflammasome agonist with an EC50 of 1.28 μM. (patent WO2018152396A1).
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15 Cited Publications
Cat. No.: HY-N0360
CAS No.: 87205-99-0
Category:
Cardiovascular Disease Quinones Samanea saman (Jacq.) Merr. Plants Phenanthrenequinones Disease Research Fields Labiatae Extract
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14
14 Cited Publications
Synonyms: 6-Hydroxyapigenin; 4',5,6,7-Tetrahydroxyflavone
Category:
Flavonoids Flavones Phenols Polyphenols Plants Disease Research Fields Medicago truncatula Gaertn. Cancer Labiatae Extract
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14
Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands .
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13 Cited Publications
Synonyms: [6]-Shogaol; 6-Shogaol
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Zingiber officinale Roscoe Monophenols Zingiberaceae Extract Phenols Plants Disease Research Fields Cancer
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13
13 Cited Publications
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CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38 .
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12 Cited Publications
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Heme Oxygenase-1-IN-1 (Compound 2) hydrochloride is a heme oxygenase 1 (HO-1) inhibitor with an IC50 of 0.25 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
