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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10357 Results for "
dimer-based compound
" in MedChemExpress (MCE) Product Catalog:
Products (10357)
10357 Results for "dimer-based compound" in MCE Product Catalog:
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12 Cited Publications
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S26131 (compound 5) is a potent and selective MT1 melatoninergic ligand, and the Ki values are 0.5 and 112 nM for MT1 and MT2, respectively. S26131 behaves as an MT1 and MT2 antagonist .
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Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts .
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11 Cited Publications
STAT3-IN-1 (compound 7d) is an excellent, selective and orally active STAT3 inhibitor, with IC50 values of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 (compound 7d) induces tumor cells apoptosis .
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11 Cited Publications
Synonyms: AQ4N dihydrochloride
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Banoxantrone dihydrochloride is a novel bioreductive agent that can be reduced to a stable, DNA-affinic compound AQ4, which is a potent topoisomerase II inhibitor.
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11 Cited Publications
YAP/TAZ inhibitor-1 is a YAP/TAZ inhibitor extracted from patent WO2017058716A1, Compound 1, has an IC50 of <0.100 μΜ in firefly luciferase assay .
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10 Cited Publications
Cat. No.: HY-D0844
CAS No.: 27025-41-8
Synonyms: L-Glutathione oxidized; GSSG; Oxiglutatione
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Category:
Microorganisms Ketones, Aldehydes, Acids Acacia catechu (Linn. f.) Willd. Phenols Polyphenols Leguminosae Extract Plants
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10 Cited Publications
Wnt/β-catenin agonist 1 (compound 3f) is a Wnt/β-catenin signalling pathway agonist, with an EC50 of 0.27 μM .
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9 Cited Publications
Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor. Clotrimazole has antibacterial activity.
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9 Cited Publications
Cat. No.: HY-N0509
CAS No.: 29838-67-3
Category:
Flavanonols Flavonoids Microorganisms Phenols Polyphenols Plants Other Families Extract Disease Research Fields Cancer
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9 Cited Publications
Synonyms: Hexadecylpyridinium chloride monohydrate
Cetylpyridinium chloride monohydrate is a cationic quaternary ammonium compound used in some types of mouthwashes, toothpastes, and throat and nasal sprays as an antiseptic that kills bacteria and other microorganisms. Effectively prevents plaque and reduces gingivitis.
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8 Cited Publications
Synonyms: Poly-p-methoxyphenethylmethylamine
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Compound 48/80 (Poly-p-methoxyphenethylmethylamine) is widely used in animal and tissue models as a "selective" mast cell activator. Compound 48/80 acts at the mast cell membrane to stimulate trimeric G-proteins and induces degranulation via phospholipase C and D pathways .
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8 Cited Publications
Synonyms: C48/80 trihydrochloride
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Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .
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8 Cited Publications
Cat. No.: HY-D0824
CAS No.: 477908-53-5
Synonyms: Sulfo-Cyanine7 Succinimidyl Ester
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Telacebec (Q203) is a midazopyridine amide compound. Telacebec is active against Mycobacterium tuberculosis H37Rv with an MIC50 of 2.7 nM in culture broth medium.
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Glimepiride (Glimperide) is a medium-to-long acting sulfonylurea anti-diabetic compound with an ED50 of 182 μg/kg. Glimepiride acts at ATPase-dependent potassium channels in β cells of the pancreas to stimulate insulin release.
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7 Cited Publications
Synonyms: Cyanine3 NHS ester
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Category:
Ketones, Aldehydes, Acids Other Diseases Chenopodiaceae Extract Beta vulgaris Linn. Plants Disease Research Fields
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
