10357 Results for "

dimer-based compound

" in MedChemExpress (MCE) Product Catalog:
Products (10357)

10357 Results for "dimer-based compound" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-100445
CAS No.: 1689540-62-2
Purity:  99.51%
Target:  

Integrin

Research Areas:  

Cardiovascular Disease Cancer

αvβ1 integrin-IN-1 (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects .
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7
7 Cited Publications
Cat. No.: HY-100445A
Purity:  98.28%
Target:  

Integrin

Research Areas:  

Cardiovascular Disease Cancer

αvβ1 integrin-IN-1 TFA (Compound C8) is a potent and selective αvβ1 integrin inhibitor with an IC50 of 0.63 nM. Antifibrotic effects .
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7
7 Cited Publications
Cat. No.: HY-10167A
CAS No.: 177172-49-5
Purity:  99.66%
Synonyms: R-568 hydrochloride; NPS R-568
Target:  

CaSR

Research Areas:  

Others

Tecalcet Hydrochloride (R 568 Hydrochloride), an orally active calcimimetic compound, allosterically and positively modulates the calcium-sensing receptor (CaSR). Tecalcet Hydrochloride (R 568 Hydrochloride) increases the sensitivity to activation by extracellular Ca 2+ .
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6
6 Cited Publications
Cat. No.: HY-103362
CAS No.: 1313730-14-1
Purity:  99.91%
Synonyms: Teijin compound 1 hydrochloride
Target:  

CCR

Research Areas:  

Inflammation/Immunology

CCR2 antagonist 4 hydrochloride (Teijin compound 1 hydrochloride) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 hydrochloride potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM .
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6
6 Cited Publications
Cat. No.: HY-108323
CAS No.: 226226-39-7
Purity:  100.0%
Synonyms: Teijin compound 1
Target:  

CCR

Research Areas:  

Inflammation/Immunology

CCR2 antagonist 4 (Teijin compound 1) is a potent and specific CCR2 antagonist, with IC50s of 180 nM for CCR2b. CCR2 antagonist 4 potently inhibits MCP-1-induced chemotaxis with an IC50 of 24 nM .
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6
6 Cited Publications
Cat. No.: HY-17461
CAS No.: 53-06-5
Synonyms: 17-Hydroxy-11-dehydrocorticosterone; Kendall's compound E
Cortisone (17-Hydroxy-11-dehydrocorticosterone), an oxidized metabolite of Cortisol (a Glucocorticoid). Cortisone acts as an immunosuppressant and anti-inflammatory agent. Cortisone can partially intervene in binding of Glucocorticoid to Glucocorticoid-receptor at high concentrations .
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6
6 Cited Publications
Cat. No.: HY-15934
CAS No.: 7240-90-6
Synonyms: BCIG
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .
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6
6 Cited Publications
Cat. No.: HY-N0748
CAS No.: 39011-91-1
Oxypaeoniflorin, an anti-oxidant, is a monoterpene glycoside compound isolated from Paeoniae species. Oxypaeoniflorin has neuroprotective and anti-inflammatory effects .
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6
6 Cited Publications
Cat. No.: HY-N0205
CAS No.: 129741-57-7
Synonyms: Anemoside B4
Pulchinenoside C (Anemoside B4) is a natural compound of the herbaceous peony saponin B4, which has many biological effects, such as antitumor, neuroprotective, and anti-angiogenic activities.
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6
6 Cited Publications
Cat. No.: HY-17035
CAS No.: 117704-25-3
Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model .
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6
6 Cited Publications
Cat. No.: HY-100597
CAS No.: 8047-15-2
Purity:  98.36%
Synonyms: Saponin
Saponins (Saponin) is a class of chemical compound of glycosides found in particular abundance in various plant species. In plants, Saponins may serve as anti-feedants, and to protect the plant against microbes and fungi .
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6
6 Cited Publications
Cat. No.: HY-10704
CAS No.: 612530-44-6
Purity:  99.65%
Synonyms: PTP1B inhibitor
PTP1B-IN-1 (Compound 7a) is a small molecule inhibitor of PTP1B with an IC50 value of 1.6 mM. It is often used as the mother core for derivatives of analogues .
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6
6 Cited Publications
Cat. No.: HY-N1318
CAS No.: 19103-54-9
Synonyms: Psathyrotin
Salvigenin is a natural polyphenolic compound, with neuroprotective effect. Salvigenin has antitumor cytotoxic and immunomodulatory properties. Salvigenin inhibits H2O2-induced cell apoptosis .
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5
5 Cited Publications
Cat. No.: HY-N0904
CAS No.: 39262-14-1
Synonyms: Ginsenoside compound K; Ginsenoside K
Ginsenoside C-K, a bacterial metabolite of G-Rb1, exhibits anti-inflammatory effects by reducing iNOS and COX-2. Ginsenoside C-K exhibits an inhibition against the activity of CYP2C9 and CYP2A6 in human liver microsomes with IC50s of 32.0±3.6 μM and 63.6±4.2 μM, respectively.
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5
5 Cited Publications
Cat. No.: HY-14430
CAS No.: 1193314-23-6
Purity:  99.90%
Synonyms: NITD609; KAE609
Target:  

Parasite

Research Areas:  

Infection

Cipargamin (NITD609) is an potent antimalarial compound, with an IC50 of appr 1 nM against P. falciparum.
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5
5 Cited Publications
Cat. No.: HY-153585
CAS No.: 2563892-44-2
Purity:  99.39%
Target:  

YAP

Research Areas:  

Cancer

IK-930 (compound I-32) is a potent and orally active TEAD inhibitor with an EC50 value of <0.1 µM .
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5
5 Cited Publications
Cat. No.: HY-124861
CAS No.: 522649-59-8
Purity:  99.69%
Synonyms: ME1
Research Areas:  

Metabolic Disease Cancer

Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM .
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5
5 Cited Publications
Cat. No.: HY-N1376
CAS No.: 38243-03-7
Synonyms: (20R)-Propanaxadiol; R-ginsenoside Rg3
(20R)-ginsenoside Rg3 ((20R)-Propanaxadiol), one of the active compounds present in ginseng root, inhibits angiogenesis, and has anti-carcinogenic and antimetastatic effects .
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5
5 Cited Publications
Cat. No.: HY-124493
CAS No.: 569-58-4
Synonyms: ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium
Aluminon (ATA; Ammonium aurintricarboxylate; Aurintricarboxylic acid ammonium) is a complexometric titration indicator and can also be used as a nuclease inhibitor affecting transfection. Aluminon is a kind of biological materials or organic compounds that are widely used in life science research .
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4
4 Cited Publications
Cat. No.: HY-139319
CAS No.: 227010-33-5
Purity:  99.88%
Target:  

Lactate Dehydrogenase

Research Areas:  

Cancer

LDHA-IN-3 (compound 2), as a selenobenzene compound, is a potent, noncompetitive lactate dehydrogenase (LDHA) inhibitor (IC50=145.2 nM). LDHA-IN-3 can be used for the research of cancer .
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