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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
73 Results for "
divalent
" in MedChemExpress (MCE) Product Catalog:
Products (73)
73 Results for "divalent" in MCE Product Catalog:
Research Areas:
Acetate kinase (ACK) is an enzyme widely distributed in bacteria and archaea. In the presence of ATP and divalent cations, it catalyzes the phosphorylation of acetate and promotes the production of acetyl-CoA. Often used in biochemical research .
Cat. No.: HY-W012898
CAS No.: 95-45-4
Synonyms: Biacetyl dioxime
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Dimethylglyoxime (Biacetyl dioxime) is an oxime compound. Dimethylglyoxime selectively coordinates with divalent nickel ions Ni 2+ to form stable complexes, and can also coordinate with copper ions Cu 2+, but does not coordinate with iron, selenium or zinc. Dimethylglyoxime inhibits the aggregation of human β-amyloid 40 peptide in vitro. Dimethylglyoxime is used in the research of Alzheimer's disease .
Cat. No.: HY-W012071
CAS No.: 16652-71-4
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(S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is an intermediate in the synthesis of L-proline derivative peptides. (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride is a key raw material for the synthesis of apoptosis inhibitor protein (IAP) antagonists and SMAC mimic tripeptide fragments (Boc-MeAla-Tle-Pro-OH). (S)-Benzyl pyrrolidine-2-carboxylate hydrochloride can be used to synthesize divalent quinazoline IAP antagonists .
Cat. No.: HY-W587753
CAS No.: 22601-59-8
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Cat. No.: HY-158222A
Synonyms: AlgMA (MW 300000)
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Alginate Methacryloyl (MW 300000) is a methacryloyl alginate with potential for use as a tissue engineering scaffold and 3D printing ink. Alginate Methacryloyl (MW 300000) is biocompatible, non-immunogenic, has low toxicity and is capable of physical cross-linking with divalent cations such as calcium . Alginate Methacryloyl (MW 300000) needs to self-assemble into fibrous hydrogel under the action of photoinitiator LAP (HY-44076), and target bioactive adhesion sites, play an inherent supporting role for tissue cells and biodegradable activity.
Application: cell culture, biological 3D printing, tissue engineering, etc.
Application: cell culture, biological 3D printing, tissue engineering, etc.
Synonyms: GPDH, rabbit muscle; α-Glycerophosphate dehydrogenase, rabbit muscle; Glycerol phosphate dehydrogenase, rabbit muscle
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Glycerol‑3‑phosphate dehydrogenase, rabbit muscle (GPDH; α-Glycerophosphate dehydrogenase; Glycerol phosphate dehydrogenase) is an NADH-dependent oxidoreductase derived from rabbit muscle that participates in glycolysis, gluconeogenesis, and the glycerol‑3‑phosphate shuttle metabolic pathway. Glycerol‑3‑phosphate dehydrogenase, rabbit muscle uses NADH as a reducing equivalent donor, and its substrate binding relies on the phosphate-binding site in the active center; it catalyzes the reversible reduction of dihydroxyacetone phosphate to L‑α‑glycerol‑3‑phosphate. The catalytic activity of the enzymatic reaction of Glycerol‑3‑phosphate dehydrogenase, rabbit muscle is regulated by pH and divalent metal ions. Glycerol‑3‑phosphate dehydrogenase, rabbit muscle can be used in metabolism-related studies .
Cat. No.: HY-158222
Synonyms: AlgMA (MW 50000)
Application: cell culture, biological 3D printing, tissue engineering, etc.
Cat. No.: HY-W105699
CAS No.: 13235-36-4
Synonyms: Ethylenediaminetetraacetic acid tetrasodium tetrahydrate
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EDTA tetrasodium tetrahydrate is a metal chelator (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. EDTA tetrasodium tetrahydrate decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. EDTA tetrasodium tetrahydrate can also decrease the formation of disulfide bonds .
Cat. No.: HY-Y0682S1
CAS No.: 203805-96-3
Synonyms: EDTA-d16
Cat. No.: HY-W110925
CAS No.: 1324-80-7
Synonyms: GPDH, microorganism; α-Glycerophosphate dehydrogenase, microorganism; Glycerol phosphate dehydrogenase, microorganism
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Glycerol-3-phosphate dehydrogenase, microorganism (GPDH; α-Glycerophosphate dehydrogenase; Glycerol phosphate dehydrogenase) is an NADH-dependent oxidoreductase derived from microorganism that participates in glycolysis, gluconeogenesis, and the glycerol‑3‑phosphate shuttle metabolic pathway. Glycerol-3-phosphate dehydrogenase, microorganism uses NADH as a reducing equivalent donor, and its substrate binding relies on the phosphate-binding site in the active center; it catalyzes the reversible reduction of dihydroxyacetone phosphate to L‑α‑glycerol‑3‑phosphate. The catalytic activity of the enzymatic reaction of Glycerol-3-phosphate dehydrogenase, microorganism is regulated by pH and divalent metal ions. Glycerol-3-phosphate dehydrogenase, microorganism can be used in metabolism-related studies .
Cat. No.: HY-W151629A
CAS No.: 1266615-85-3
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Ferrozine sodium hydrate is a spectrophotometric reagent for iron, can react with divalent Fe to form a stable magenta complex species. The complex has an absorption peak at 562 nm .Ferrozine sodium hydrate-based colorimetric assays can quantify iron in cells
Synonyms: L-Cysteinylglycine TFA; Cys-Gly TFA; H-Cys-Gly-OH TFA
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Phosphorylase b is one of the two forms of phosphorylase present in skeletal muscle. The other is Phosphorylase a, which can be transformed into one another. The conversion process requires the addition of divalent metal ions and ATP .
Cat. No.: HY-D1640
CAS No.: 152290-47-6
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5,5'-Difluoro BAPTA tetrapotassium is a difluoro-derivative of BAPTA (HY-100168). 5,5'-Difluoro BAPTA tetrapotassium shows large 19F NMR chemical shifts upon chelating divalent cations. 5,5'-Difluoro BAPTA tetrapotassium has high selectivity for Ca 2+. 5,5'-Difluoro BAPTA tetrapotassium can inhibit the growth of pollen tube .
Cat. No.: HY-N6687B
CAS No.: 72124-77-7
Synonyms: A-23187 hemimagnesium; Antibiotic A-23187 hemimagnesium
Calcimycin (A-23187) hemimagnesium is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin hemimagnesium induces Ca 2+-dependent cell death by increasing intracellular calcium concentration. Calcimycin hemimagnesium inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin hemimagnesium also inhibits the activity of ATPase and uncouples oxidative phosphorylation (OXPHOS) of mammalian cells. Calcimycin hemimagnesium induces apoptosis and autophagy .
Cat. No.: HY-121858
CAS No.: 34441-14-0
Cat. No.: HY-159888
CAS No.: 3034673-37-2
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SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research .
Cat. No.: HY-W540926
CAS No.: 75006-64-3
Synonyms: Biacetyl dioxime sodium hydrate
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Dimethylglyoxime sodium hydrate (Biacetyl dioxime sodium hydrate) is an oxime compound. Dimethylglyoxime sodium hydrate selectively coordinates with divalent nickel ions Ni 2+ to form stable complexes, and can also coordinate with copper ions Cu 2+, but does not coordinate with iron, selenium or zinc. Dimethylglyoxime sodium hydrate inhibits the aggregation of human β-amyloid 40 peptide in vitro. Dimethylglyoxime sodium hydrate is used in the research of Alzheimer's disease .
Cat. No.: HY-124703
CAS No.: 65004-42-4
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Pyrimidinone 8 is a reversible linear non-competitive inhibitor of divalent metal transporter 1 (DMT1), with a Ki of 20 μM (hDMT1). Pyrimidinone 8 does not affect hDMT1 cell surface expression and shows no dependence with the extracellular pH. Pyrimidinone 8 can inhibit hDMT1-mediated iron uptake, with an IC50 of 13.8 μM .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
