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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
238 Results for "
fluorogenicity
" in MedChemExpress (MCE) Product Catalog:
Products (238)
238 Results for "fluorogenicity" in MCE Product Catalog:
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1 Cited Publications
Synonyms: Fluorogenic Proteasome Substrate; Z-ARR-AMC
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Cat. No.: HY-P5983
CAS No.: 210345-01-0
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1 Cited Publications
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4-Methylumbelliferyl-2-acetamido-2-deoxy-β-D-Glucopyranoside is a fluorogenic substrate for N-acetyl-β-D-glucosaminidase .
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Cat. No.: HY-134432B
Purity: 99.69%
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1 Cited Publications
Cat. No.: HY-P5354
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1 Cited Publications
Cat. No.: HY-119977
CAS No.: 359010-70-1
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APF is a cell-permeable fluorogenic probe to measure hydroxyly radical of ROS. APF is nonfluorescent and produces bright green fluorescence upon reaction with hydroxyl radical. APF can be used to detect intracellular reactive oxygen species (ROS) (Ex/Em=490/525 nm) .
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Cat. No.: HY-P4406
CAS No.: 100307-95-7
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1 Cited Publications
Cat. No.: HY-W016288
CAS No.: 7149-49-7
Synonyms: 2,3-Naphthalenedicarboxaldehyde; Naphthalene-2,3-dialdehyde
Naphthalene-2,3-dicarboxaldehyde (NDA) is an effective inhibitor of Candida albicans aspartate semialdehyde dehydrogenase (ASADH), with a Ki value of 45 μM. Naphthalene-2,3-dicarboxaldehyde targets ASADH in the aspartate biosynthetic pathway of Candida albicans. Naphthalene-2,3-dicarboxaldehyde reacts with primary amines to generate highly fluorescent and stable derivatives. Naphthalene-2,3-dicarboxaldehyde serves as a fungistatic agent and a fluorogenic derivatization reagent. Naphthalene-2,3-Dicarboxaldehyde can be used for the research of candidiasis .
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Z-Leu-Arg-AMC is a fluorogenic peptide substrate for cysteine proteases (e.g., Cathepsin) (Ex=350 nm，Em=460 nm). Z-Leu-Arg-AMC is preferentially cleaved by Cathepsin K and S under weakly acidic conditions, while its hydrolysis relies on residual Cathepsin S activity at neutral pH. Z-Leu-Arg-AMC serves as a substrate for recombinant Sphenophorus levis Cathepsin L, falcipain-2, falcipain-3, berghepain-2, knowlepain-2, vivapain-2, as well as falcipain-2 chimeras and constructs. It enables quantitative detection of cysteine protease activity in human inflammatory bronchoalveolar lavage fluid via fluorescence generation. Z-Leu-Arg-AMC can be used in research related to pulmonary inflammatory diseases and malaria .
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Cat. No.: HY-P4326
CAS No.: 65147-04-8
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Cat. No.: HY-P2179
CAS No.: 150956-92-6
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MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic peptide substrate that can be cleaved by active MMP-1/9, thereby enabling measurement of their enzymatic activity. Ex/Em=340/440 nm .
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Cat. No.: HY-160289
CAS No.: 1426305-25-0
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ARI-3144 is a fluorogenic substrate for FAP with a FAP/PREP selectivity index of 15, and is processed by prolyl oligopeptidase (PREP) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
