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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
95 Results for "
IL5
" in MedChemExpress (MCE) Product Catalog:
Products (95)
95 Results for "IL5" in MCE Product Catalog:
Cat. No.: HY-P990058
CAS No.: 2643349-04-4
Target:
Research Areas:
Cat. No.: HY-19472
CAS No.: 287183-00-0
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RWJ-58643 is a β-trypsin inhibitor that suppresses allergic inflammation. RWJ-58643 (100 mg) significantly reduced nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 resulted in late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 modulates allergic responses by inhibiting the release of β-trypsin from mast cells .
Cat. No.: HY-19472A
CAS No.: 287182-52-9
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RWJ-58643 hydrochloride is a β-trypsin inhibitor that inhibits allergic inflammation. RWJ-58643 hydrochloride (100 mg) significantly reduces nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 hydrochloride causes late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 hydrochloride modulates allergic reactions by inhibiting the release of β-trypsin from mast cells.
Cat. No.: HY-P991599
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Research Areas:
Cat. No.: HY-169864
CAS No.: 1137536-21-0
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KRO-105714 is the antagonist for sphingosine phosphocholine receptor (SPC Receptor) and sphingosine-1-phosphate receptor 1 (S1P1 Receptor) (IC50=79.2 nM). KRO-105714 inhibits SPC-induced proliferation of NIH3T3 (IC50=5.6 nM), inhibits SPC-induced cell migration (IC50=0.59 μM) and tube formation in HUVECs. KRO-105714 inhibits SPC-induced generation of IL-4 and IL-5, exhibits anti-inflammtory efficacy in mouse atopic dermatitis models .
Cat. No.: HY-165484
CAS No.: 459805-03-9
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AVP-13358 is an orally active IgE inhibitor that effectively suppresses immunoglobulin E (IgE)-mediated immune responses, with IC50 values of 8 and 3 nM for IgE inhibition in vivo and in vitro in BALB/c mice, respectively. AVP-13358 acts directly on T cells, inhibiting the production and release of IL-4, IL-5, and IL-13. It also targets other markers critical for the development of allergic responses, including the B cell IgE receptor (CD23) in human monocytes and the CD23 and IL-4 receptors in mouse B cells. AVP-13358 can be used in research related to anti-allergic responses .
Cat. No.: HY-N0646R
CAS No.: 29782-68-1
Cat. No.: HY-P78608
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:
Rabbit
Source:
HEK293
Cat. No.: HY-P71630
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:
Pig
Source:
E. coli
Cat. No.: HY-174601
Target:
Research Areas:
Human IL5RA mRNA encodes the human interleukin 5 receptor subunit alpha (IL5RA) protein, an interleukin 5 specific subunit of a heterodimeric cytokine receptor. IL5RA has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4.
Cat. No.: HY-P700131AF
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:
Human
Source:
E. coli
Cat. No.: HY-P990452
Target:
Research Areas:
Cat. No.: HY-P72387
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:
Human
Source:
HEK293
Cat. No.: HY-P73219
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P73218
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:
Canine
Source:
Sf9 insect cells
Cat. No.: HY-P73878
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:
Cynomolgus
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
