10020 Results for "

water-soluble modified polyether

" in MedChemExpress (MCE) Product Catalog:
Products (10020)

10020 Results for "water-soluble modified polyether" in MCE Product Catalog:

7
7 Cited Publications
Cat. No.: HY-100236
CAS No.: 374913-63-0
Purity:  99.17%
Synonyms: DDD00107587
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Madrasin (DDD00107587) is a splicing inhibitor that prevents formation of both splicing intermediates and products in vitro and interferes with one or more early steps in the pathway of spliceosome assembly. Madrasin also can inhibit pre-mRNA splicing in vitro and modify splicing of endogenous pre-mRNA in cells .
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6
6 Cited Publications
Cat. No.: HY-B0717
CAS No.: 9002-96-4
Synonyms: TPGS; D-α-Tocopherol polyethylene glycol 1000 succinate; Vitamin E-TPGS
Tocofersolan is synthetic polyethylene glycol derivative of α-tocopherol. Tocofersolan is an orally active and water-soluble analog of vitamin E. Tocofersolan can reduce neurobehavioral deficits in zebrafish embryos exposed to moderate and high concentrations of BaP during early development. Tocofersolan shows antioxidant activity. Tocofersolan can be used to provide an orally bioavailable source of vitamin E .
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5
5 Cited Publications
Cat. No.: HY-B0594
CAS No.: 66108-95-0
Target:  

Autophagy Mitophagy

Research Areas:  

Cancer

Iohexol is a non-ionic, water-soluble contrast agent used as a reference marker for the determination of glomerular filtration rate (GFR) at the level of renal function. Iohexol can be used for contrast in myelography, computerized tomography (cisternography, ventriculography) and MicroCT imaging .
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5
5 Cited Publications
Cat. No.: HY-136976
CAS No.: 150849-52-8
Purity:  ≥98.0%
WST-1 is a kind of water-soluble tetrazolium salt. WST induces the intracellular mitochondrial dehydrogenase to conduct NADH-dependent enzyme digestion reaction, releasing the water-soluble methyl benzene product. WST-1 can be used for the detection of cell proliferation and cytotoxicity, via the determination of the light absorption value at 450 nm .
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5
5 Cited Publications
Cat. No.: HY-17558
CAS No.: 37321-09-8
Synonyms: Nebramycin II
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Apramycin (Nebramycin II) is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin is a potential anti-drug-resistance antibiotic .
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5
5 Cited Publications
Cat. No.: HY-B1329
CAS No.: 65710-07-8
Synonyms: Nebramycin II sulfate
Apramycin (EBL 1003) sulfate is an orally active, acidic pH tolerant and aminoglycoside-modifying-enzymes-tolerant aminoglycoside antibiotic which inhibits protein biosynthesis by targeting the bacterial ribosome. Apramycin sulfate is a potential anti-drug-resistance antibiotic .
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5
5 Cited Publications
Cat. No.: HY-P99720
CAS No.: 1373715-00-4
Synonyms: ACE-536; luspatercept–aamt
Target:  

TGF-beta/Smad

Research Areas:  

Cardiovascular Disease

Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia .
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5
5 Cited Publications
Cat. No.: HY-17638
CAS No.: 666843-10-3
Synonyms: DSP-3235 free base; KGA-3235 free base; GSK-1614235 free base
Target:  

SGLT

Research Areas:  

Metabolic Disease

Mizagliflozin (DSP-3235 free base) is a potent, orally active and selective SGLT1 inhibitor, with a Ki of 27 nM for human SGLT1. Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic agent that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation .
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4
4 Cited Publications
Cat. No.: HY-122131
CAS No.: 111072-31-2
Purity:  99.90%
Research Areas:  

Others

XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product.
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4
4 Cited Publications
Cat. No.: HY-D0034
CAS No.: 307554-62-7
Synonyms: ABMDMA
9,10-Anthracenediyl-bis(methylene)dimalonic acid (ABMDMA) is a biological dye and indicator used to detect singlet oxygen generation (SOG). 9,10-Anthracenediyl-bis(methylene)dimalonic acid is water-soluble derivative of anthracene. 9,10-Anthracenediyl-bis(methylene)dimalonic acid can be photobleached by singlet oxygen to its corresponding endoperoxide. This reaction can be monitored spectrophotometrically by recording the decrease of absorbance at 400 nm .
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4
4 Cited Publications
Cat. No.: HY-115400
CAS No.: 1062444-54-5
Purity:  99.67%
Synonyms: TLR7 agonist T7
Research Areas:  

Cancer

1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects. 1V209 can be conjugated with various polysaccharides to improve its water solubility, and enhance its efficacy, and maintain low toxicity .
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4
4 Cited Publications
Cat. No.: HY-52101A
CAS No.: 821794-92-7
Research Areas:  

Cancer

FMK is a an irreversible RSK2 kinase inhibitor, that covalently modifies the C-terminal kinase domain of RSK.
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3
3 Cited Publications
Cat. No.: HY-Y0850H
CAS No.: 9002-89-5
Synonyms: PVA (Mw 89000-98000, 99+% hydrolyzed); Poly(Ethenol) (Mw 89000-98000, 99+% hydrolyzed)
Polyvinyl alcohol (Mw 89000-98000, 99+% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics .
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3
3 Cited Publications
Cat. No.: HY-Y0850N
CAS No.: 9002-89-5
Synonyms: PVA (Mw 13000-23000, 98% hydrolyzed); Poly(Ethenol) (Mw 13000-23000, 98% hydrolyzed)
Polyvinyl alcohol (PVA; Poly(Ethenol)) (Mw 13000-23000, 98% hydrolyzed) , also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 13000-23000, 98% hydrolyzed) can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol (Mw 13,000–23,000, 98% hydrolyzed) can be used in studies involving breast cancer as well as cisplatin (HY-17394)-induced sensorineural hearing loss .
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3
3 Cited Publications
Cat. No.: HY-Y0850K
CAS No.: 9002-89-5
Synonyms: PVA (Mw 31000-50000, 98-99% hydrolyzed); Poly(Ethenol) (Mw 31000-50000, 98-99% hydrolyzed)
Polyvinyl alcohol (Mw 31000-50000, 98-99% hydrolyzed), also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. It can also be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .
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3
3 Cited Publications
Cat. No.: HY-Y0850I
CAS No.: 9002-89-5
Synonyms: PVA (Mw 9000-10000, 80% hydrolyzed); Poly(Ethenol) (Mw 9000-10000, 80% hydrolyzed)
Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) also known as PVA, is a vinyl water-soluble polymer that can be used as a non-ionic surfactant. Polyvinyl alcohol (Mw 9000-10000, 80% hydrolyzed) can be used as a biodegradable polymer and can be used in adhesives, coatings, textiles, ceramics, and cosmetics. Polyvinyl alcohol can be used in tissue engineering by electrospinning. Polyvinyl alcohol can achieve high cellular density, infiltration, and uniform distribution, facilitating functional connections between cells. Polyvinyl alcohol can improve cell vitality through in vitro cultivation. Polyvinyl alcohol demonstrates promising inhibition of ostersarcoma cancer cells with Doxorubicin (HY-15142A) .
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3
3 Cited Publications
Cat. No.: HY-100528
CAS No.: 65101-87-3
Purity:  99.67%
Synonyms: Nanchangmycin A
Nanchangmycin, a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria . Nanchangmycin is a broad spectrum antiviral active against Zika virus .
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3
3 Cited Publications
Cat. No.: HY-100528A
CAS No.: 35865-33-9
Purity:  99.67%
Synonyms: Nanchangmycin free acid
Dianemycin (Nanchangmycin free acid), a polyether antibiotic produced by Streptomyces nanchangensis NS3226, inhibits gram-positive bacteria . Nanchangmycin is a broad spectrum antiviral active against Zika virus .
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3
3 Cited Publications
Cat. No.: HY-D0926
CAS No.: 847180-48-7
Target:  

Fluorescent Dye

Research Areas:  

Others

Cy7.5 is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
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3
3 Cited Publications
Cat. No.: HY-103641
CAS No.: 1391194-67-4
Purity:  99.91%
Synonyms: (2R)-Octyl-2-HG
Target:  

Drug Isomer

Research Areas:  

Cancer

(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate.
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