95 Results for "

IL5

" in MedChemExpress (MCE) Product Catalog:
Products (95)

95 Results for "IL5" in MCE Product Catalog:

製品番号: HY-P990058
CAS 番号: 2643349-04-4

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

Varokibart (TEV-53275) is a human IgG4λ antibody targeting IL5 .
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製品番号: HY-19472
CAS 番号: 287183-00-0
Target:  

Ser/Thr Protease

研究分野:  

Inflammation/Immunology

RWJ-58643 is a β-trypsin inhibitor that suppresses allergic inflammation. RWJ-58643 (100 mg) significantly reduced nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 resulted in late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 modulates allergic responses by inhibiting the release of β-trypsin from mast cells .
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製品番号: HY-19472A
CAS 番号: 287182-52-9
Target:  

Ser/Thr Protease

研究分野:  

Inflammation/Immunology

RWJ-58643 hydrochloride is a β-trypsin inhibitor that inhibits allergic inflammation. RWJ-58643 hydrochloride (100 mg) significantly reduces nasal allergy symptoms, eosinophil infiltration, and IL-5 levels at low doses. RWJ-58643 hydrochloride causes late eosinophilia and elevated IL-5 levels at high doses (300 mg and 600 mg). RWJ-58643 hydrochloride modulates allergic reactions by inhibiting the release of β-trypsin from mast cells.
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製品番号: HY-P991599

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

SHR-1703 is a long-acting humanized anti-IL-5 IgG1 monoclonal antibody. SHR-1703 can selectively recognize and bind to IL-5, blocking the binding of IL-5 to the α chain of the receptor on the surface of eosinophils, thereby inhibiting the proliferation, activation, and migration of eosinophils, and ultimately reducing eosinophil-mediated inflammation and damage. SHR-1703 can be used in the research of eosinophil-related diseases, such as eosinophilic asthma. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) .
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製品番号: HY-N8309R
CAS 番号: 6920-38-3
Luteolin-4'-O-glucoside (Standard) is the analytical standard of Luteolin-4'-O-glucoside. This product is intended for research and analytical applications. Luteolin-4'-O-glucoside is an IL-5 inhibitor with an IC50 of 3.7 μM. Luteolin-4'-O-glucoside resists hyperuricemia and acute gouty arthritis activity. Luteolin-4'-O-glucoside shows anticancer activity .
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製品番号: HY-N6013R
CAS 番号: 8015-61-0
Aloin (mixture of A&B) (Standard) is the analytical standard of Aloin (mixture of A&B) (HY-N6013). This product is intended for research and analytical applications. Aloin (mixture of A&B) is an orally active anthraquinone derivative isolated from Aloe vera. Aloin (mixture of A&B) mitigates airway impairment and exerts neuroprotective, anti-inflammatory, antioxidant, antibacterial, antifungal, antiviral and antitumor effects. Aloin (mixture of A&B) inhibits Clostridium histolyticum collagenase, granulocyte matrix metalloproteinases and human 20S proteasome. Aloin (mixture of A&B) upregulates the Nrf2/HO-1 pathway, suppresses the TGF-β/Smad2/3 pathway. Aloin (mixture of A&B) reduces IL-4/IL-5/IL-13 levels, and reverses oxidative stress markers (MDA, SOD, GSH). Aloin (mixture of A&B) can be used for research on chronic ulcers, burns, wounds, inflammatory and degenerative disorders, asthma and neuroblastoma .
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製品番号: HY-169864
CAS 番号: 1137536-21-0
Target:  

LPL Receptor

研究分野:  

Inflammation/Immunology

KRO-105714 is the antagonist for sphingosine phosphocholine receptor (SPC Receptor) and sphingosine-1-phosphate receptor 1 (S1P1 Receptor) (IC50=79.2 nM). KRO-105714 inhibits SPC-induced proliferation of NIH3T3 (IC50=5.6 nM), inhibits SPC-induced cell migration (IC50=0.59 μM) and tube formation in HUVECs. KRO-105714 inhibits SPC-induced generation of IL-4 and IL-5, exhibits anti-inflammtory efficacy in mouse atopic dermatitis models .
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製品番号: HY-165484
CAS 番号: 459805-03-9
Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

AVP-13358 is an orally active IgE inhibitor that effectively suppresses immunoglobulin E (IgE)-mediated immune responses, with IC50 values of 8 and 3 nM for IgE inhibition in vivo and in vitro in BALB/c mice, respectively. AVP-13358 acts directly on T cells, inhibiting the production and release of IL-4, IL-5, and IL-13. It also targets other markers critical for the development of allergic responses, including the B cell IgE receptor (CD23) in human monocytes and the CD23 and IL-4 receptors in mouse B cells. AVP-13358 can be used in research related to anti-allergic responses .
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製品番号: HY-N0646R
CAS 番号: 29782-68-1
Silydianin (Standard) is the analytical standard of Silydianin (HY-N0646). This product is intended for research and analytical applications. Silydianin is a flavonolignan. Silydianin can be obtained from Silybum marianum. Silydianin inhibits PTP1B with an IC50 of 17.38 μM. Silydianin inhibits both monophenolase and diphenolase of tyrosinase significantly, with IC50s of 2.6 μM and 16.5 μM, respectively. Silydianin induces Apoptosis and reduces cytokines (IL-4 and IL-5). Silymarin has antioxidant, cytoprotective and immunomodulatory effects. Silydianin has antitumor activity against prostate cancer. Silymarin can be used in allergic asthma research [5] .
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製品番号: HY-K2102

MCE HOLO Human Interleukin-5 (IL-5) Detection Kit is a homogeneous luminescence-based assay used for the quantitative detection of human IL-5 concentrations in biological samples such as buffer solutions, cell culture supernatants, or serum.

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製品番号: HY-P85018
別名: IL5; Interleukin-5; IL-5; B-cell differentiation factor I; EosinophIL differentiation factor; T-cell replacing factor; TRF; IL-5 nanobody;

Host:  

Mouse

Application:  

ELISA

Reactivity:  

Human

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製品番号: HY-P78608
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:  
Rabbit
Source:  
HEK293
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製品番号: HY-P71630
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:  
Pig
Source:  
E. coli
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製品番号: HY-174601
Target:  

mRNA

研究分野:  

Inflammation/Immunology

Human IL5RA mRNA encodes the human interleukin 5 receptor subunit alpha (IL5RA) protein, an interleukin 5 specific subunit of a heterodimeric cytokine receptor. IL5RA has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4.
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製品番号: HY-P700131AF
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:  
Human
Source:  
E. coli
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製品番号: HY-P990452

Target:  

Interleukin Related

研究分野:  

Inflammation/Immunology

Anti-IL-5 Antibody is a CHO-expressed humanized antibody that targets IL-5. The Anti-IL-5 Antibody is composed of huIgG4 heavy chains and huκ light chains, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-IL-5 Antibody can be referenced as Human IgG4 kappa, Isotype Control (HY-P99003).
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製品番号: HY-P72387
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:  
Human
Source:  
HEK293
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製品番号: HY-P73219
純度:  ≥ 90%, as determined by reducing SDS-PAGE.
別名: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:  
Mouse
Source:  
Sf9 insect cells
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製品番号: HY-P73218
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:  
Canine
Source:  
Sf9 insect cells
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製品番号: HY-P73878
純度:  ≥ 95%, as determined by reducing SDS-PAGE.
別名: IL5; T-Cell Replacing Factor; Interleukin 5; EDF; EosinophIL Differentiation Factor; Colony-Stimulating Factor, EosinophIL; Interleukin-5; B-Cell Differentiation Factor I; IL-5; Interleukin 5 (Colony-Stimulating Factor, EosinophIL); TRF; B Cell Differenti
Species:  
Cynomolgus
Source:  
Sf9 insect cells
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