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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
119 Results for "
S-Transferase
" in MedChemExpress (MCE) Product Catalog:
Products (119)
119 Results for "S-Transferase" in MCE Product Catalog:
Cat. No.: HY-175398
CAS No.: 2201798-21-0
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OZO-Cl is an OZO derivative. OZO-Cl has anti-cancer activity. OZO-Cl significantly decreases the intracellular glutathion S-transferase Pi (GST) activity. OZO-Cl exhibits cytotoxicity to cancer cell lines, with IC50s of 150 and 120 μmol/L in Panc-1 and K562 cells respectively .
Cat. No.: HY-W975966
CAS No.: 14085-33-7
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CPDT is an orally active and highly potent inducer of phase 2 enzymes and an activator of Nrf2. The activities of key phase 2 enzymes, including glutathione S-transferase, NAD(P)H:quinone:oxidoreductase 1 and glutamate cysteine synthetase, and levels of glutathione were elevated by CPDT in rat bladder in vivo and in cultured bladder cells in vitro [2].
Cat. No.: HY-13634
CAS No.: 286942-97-0
Synonyms: TER199; TLK199 hydrochloride
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Cat. No.: HY-W019780
CAS No.: 75-27-4
Synonyms: Dichlorobromomethane
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Bromodichloromethane (Dichlorobromomethane) is a type of trihalomethane, commonly found in chlorinated drinking water for disinfection, and is a disinfection by-product. The bromination of bromodichloromethane can cause the formation of mutagenic intermediates through the transformation mediated by glutathione S-transferase (GST). Bromodichloromethane inhibits the differentiation of human placental trophoblast cells and reduces the secretion of chorionic gonadotropin (CG). Bromodichloromethane has potential reproductive toxicity and carcinogenicity .
Cat. No.: HY-P2961B
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Glutathione S-Transferase, E.coli is a glutathione S-transferase derived from Escherichia coli. Glutathione S-Transferase, E.coli is a phase II metabolic enzyme composed of three superfamilies: cytosolic, mitochondrial, and microsomal. Glutathione S-Transferase, E.coli possesses multiple catalytic activities, including catalytic detoxification and thiol transfer, as well as molecular chaperone functions. The Glutathione S-Transferase, E.coli isoform GSTP1 is highly expressed in malignant tumors and serves as a tumor biomarker .
Cat. No.: HY-160874
CAS No.: 1358386-87-4
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GST-FH.4 is a GST-FH compound, a complex that produces frequent false positive hits (FH) in the interaction between glutathione S-transferase (GST) and glutathione (GSH) . GST-FH.4 inhibits glutathione S-transferase (GST) activity with an IC50 of 24.38 μM .
Cat. No.: HY-133199
CAS No.: 138968-85-1
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Cat. No.: HY-16123
CAS No.: 439943-59-6
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Canfosfamide (hydrochloride) is a prodrug that upon activation by glutathione s-transferase P1-1 (GSTP1-1) yields an anticancer alkylating agent and a glutathione derivative.
Cat. No.: HY-N11778
CAS No.: 152175-74-1
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Cat. No.: HY-N11699
CAS No.: 151013-37-5
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Cat. No.: HY-W100026S
Synonyms: Senecionan-11,16-dione, 12-hydroxy- (Standard); Aureine (Standard); Senecionin (Standard)
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Pterogyne nitens Tul. Alkaloids Erinacea anthyllis Link Pyrrole Alkaloids Plants Compositae Extract
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Cat. No.: HY-W154265
CAS No.: 15131-80-3
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2,2′-Dihydroxychalcone, a flavonoid, is a glutathione S-transferase (GST) inhibitor with an IC50 of 28.9 μM in human colon cancer cells. 2,2′-Dihydroxychalcone induces cell cycle arrest and apoptosis in prostate cancer cells. 2,2′-Dihydroxychalcone has anticancer and anti-inflammatory properties .
Cat. No.: HY-W017785
CAS No.: 504-20-1
Synonyms: Diisopropylidene acetone
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Cat. No.: HY-179057
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GSTA4-IN-1 (Compound 3a) is a potent and competitive inhibitor of glutathione S-transferase A4 (GSTA4), with an IC50 of 3.12 μM and a Ki of 2.38 μM. GSTA4-IN-1 is cytotoxic to colorectal cancer cells. GSTA4-IN-1 can be used for research on colorectal cancer .
Cat. No.: HY-N12261
CAS No.: 138968-86-2
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Cat. No.: HY-126752R
CAS No.: 495-27-2
Cat. No.: HY-132913
CAS No.: 2771119-22-1
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Cyclopropenone probe 1 can specifically and efficiently modify a triple-negative breast cancer driver, glutathione S-transferase pi-1 (GSTP1), by covalently binding at the catalytic active site. Cyclopropenone probe 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Ethacrynic acid (Etacrynic acid sodium) sodium is a diuretic. Ethacrynic acid sodium is an inhibitor of glutathione S-transferases (GSTs). Ethacrynic acid sodium is a potent inhibitor of NF-kB-signaling pathway, and also modulates leukotriene formation. Ethacrynic acid sodium also inhibits L-type voltage-dependent and store-operated calcium channel, leading to relaxation of airway smooth muscle (ASM) cells. Ethacrynic acid sodium has anti-inflammatory properties that reduces the retinoid-induced ear edema in mice .
Cat. No.: HY-P75152
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GSTM2; Glutathione S-AlkylTransferase M2; Glutathione S-Transferase Mu 2; Glutathione S-ArylTransferase M2; GST4; Glutathione S-Transferase M1; Glutathione S-Transferase Mu 2 (Muscle); Glutathione S-Transferase 4; Glutathione S-Transferase M2 (Muscle); Gl
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
