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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
130 Results for "
subcutaneous fibrosarcoma
" in MedChemExpress (MCE) Product Catalog:
Products (130)
130 Results for "subcutaneous fibrosarcoma" in MCE Product Catalog:
Cat. No.: HY-159508
CAS No.: 1643326-82-2
Brimarafenib is a rapidly accelerated fibrosarcoma (Raf) kinase inhibitor wtih antineoplastic effect .
Cat. No.: HY-13554
CAS No.: 92689-49-1
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Annamycin is an anthracycline antibiotic with antitumor activity. Annamycin interacts with topoisomerase II, induces double-strand DNA breaks, triggers cell death, and exerts cytotoxic effects. In mice, Annamycin inhibits the growth of advanced subcutaneous melanoma and subcutaneous squamous cell carcinoma, and prolongs the survival of mice with subcutaneous reticulosarcoma and in lung cancer lung metastasis models. Annamycin can be used in research related to melanoma, reticulum cell sarcoma, lung cancer, non-small cell lung cancer, small cell lung cancer .
Cat. No.: HY-N10158
CAS No.: 207792-17-4
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1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one (compound 39), a diarylheptanoid, exhibits antiproliferative activity towards human HT-1080 fibrosarcoma and murine colon 26-L5 carcinoma cells .
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Lignans Dysosma versipellis (Hance) M. Cheng ex Ying Phenylpropanoids Plants Berberidaceae Extract
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Cat. No.: HY-116861
CAS No.: 369358-07-6
A-357300 is a reversible and selective MetAP2 inhibitor with IC50s of 0.12 and 57 μM against MetAP2 and MetAP1. A-357300 induces cytostasis by cell cycle arrest at the G1 phase selectively in endothelial cells and in a subset of tumor cells. A-357300 inhibits angiogenesis both in vitro and in vivo and shows potent antitumor efficacy in carcinoma, sarcoma, and neuroblastoma murine models. A-357300 can be used for the studies of neuroblastoma, fibrosarcoma and breast cancer .
Cat. No.: HY-172351B
CAS No.: 24991-53-5
Cat. No.: HY-162449
CAS No.: 2942242-60-4
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GIC-20 is a dual inducer for apoptosis and ferroptosis. GIC-20 exhibits antitumor efficacy against fibrosarcoma .
Cat. No.: HY-W615797
CAS No.: 531-76-0
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DL-Sarcolysine is an alkylating agent-based antitumor agent. DL-Sarcolysine shows significant inhibitory activity against solid tumors transplanted subcutaneously and in the abdominal cavity .
Cat. No.: HY-W751579
CAS No.: 234096-34-5
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Cefovecin is a third-generation cephalosporin antibiotic. Cefovecin's most notable characteristic is its extremely long-lasting effect; a single subcutaneous injection can maintain an effective therapeutic concentration in tissues for up to 14 days. Cefovecin is used in research on bacterial infections in dogs and cats .
Cat. No.: HY-157788
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ZX703 is a GPX4 PROTAC degrader with a DC50 of 0.135 μM. ZX703 degrades GPX4 via the ubiquitin-proteasome and autophagy-lysosome pathways. ZX703 induces the accumulation of ROS, thereby triggering Ferroptosis. ZX703 can be used in studies related to fibrosarcoma and prostate cancer .
Cat. No.: HY-162106
CAS No.: 3035509-76-0
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PROTAC GPX4 degrader-2 is a cIAP-recruiting GPX4 PROTAC degrader with a DC50 of 1.68 μM. PROTAC GPX4 degrader-2 forms a ternary complex with GPX4 and cIAP, and induces GPX4 degradation via the ubiquitin-proteasome system pathway. PROTAC GPX4 degrader-2 induces Mitochondrial depolarization and Ferroptosis. PROTAC GPX4 degrader-2 exhibits antiproliferative effects in cancer cells. PROTAC GPX4 degrader-2 can be used for the research of fibrosarcoma .
Cat. No.: HY-176065
CAS No.: 3084825-09-9
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Nav1.2-IN-1 (compound 5i), a 3-(1,2,3,6-tetrahydropyridine)-4-azaindole derivative, is a potent and selective Nav1.2 inhibitor. Nav1.2-IN-1 induces a reduction in the peak amplitude of Nav1.2 currents with an IC50 value of 7.79 μM. Nav1.2-IN-1 exhibits antiepileptic activity. Nav1.2-IN-1 shows high anticonvulsant effect and low neurotoxicity in subcutaneous Pentetrazole (sc-PTZ)-induced epilepsy mode .
Cat. No.: HY-N14542
CAS No.: 12764-54-4
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Cat. No.: HY-130201
CAS No.: 138370-82-8
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Deacetylsaptomycin D is a deacetylated saptomycin with in vitro antitumor activity. Deacetylsaptomycin D inhibits the growth of mouse methoxy-A fibrosarcoma cells .
Cat. No.: HY-N3215
CAS No.: 24338-53-2
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Podocarpaceae Extract Terpenoids Diterpenoids Podocarpus sellowii Klotzsch ex Endl. Plants
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Cat. No.: HY-129661
CAS No.: 763023-14-9
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AH 7959 is an orally active N-substituted cyclohexyl methyl benzamide compound that has analgesic effects, the oral and subcutaneous ED50 of AH 7959 in mice is greater than 100 mg/kg .
Cat. No.: HY-109080A
CAS No.: 2443966-84-3
Synonyms: HM95573 TFA; GDC-5573 TFA; RG6185 TFA
Belvarafenib TFA (HM95573 TFA) is a potent and pan RAF (Rapidly Accelerated Fibrosarcoma) inhibitor, with IC50s of 56 nM, 7 nM and 5 nM for B-RAF, B-RAFv 600E and C-RAF respectively .
Cat. No.: HY-146615
CAS No.: 2642224-22-2
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Axl-IN-6 (compound 14) is an orally active and potent AXL inhibitor. Axl-IN-6 is well tolerated and significantly inhibits the tumor growth in MV-4-11 subcutaneous xenograft model .
Cat. No.: HY-100279
CAS No.: 38020-45-0
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RMI 10874 is a tilorone analogue. Tilorone is a small-molecule, orally bioavailable antiviral agent. RMI 10874 completely abolishes lung colonization of an H-2 negative (GR9.B9) MCA-induced fibrosarcoma clone.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
