120 Results for "

P388

" in MedChemExpress (MCE) Product Catalog:
Products (120)

120 Results for "P388" in MCE Product Catalog:

Cat. No.: HY-N14276
CAS No.: 497182-82-8
Miyakamide B1 is an antibiotic with insecticidal effect. Miyakamide B1 inhibits the growth of Artemia salina. Miyakamide B1 has a weak antixanthomonas activity. Miyakamide B1 inhibits P388 cells with an IC50 of 8.8 μg/mL .
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Cat. No.: HY-N14277
CAS No.: 497182-83-9
Miyakamide B2 is an antibiotic with insecticidal effect. Miyakamide B2 inhibits the growth of Artemia salina. Miyakamide B2 has a weak antixanthomonas activity. Miyakamide B2 inhibits P388 cells with an IC50 of 7.6 μg/mL .
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Cat. No.: HY-N14523
CAS No.: 195052-09-6
Gilvusmycin is an antibiotic with strong anti-tumor activity. Gilvusmycin can inhibit P388, K562, A431 and MKN28 cells with IC50s (ng/mL) of 0.08, 0.86, 0.72 and 0.75, respectively .
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Cat. No.: HY-N14747
CAS No.: 97218-42-3
Elloramycin has weak activity against Gram-positive bacteria, streptomycete and L-1210 leukemic cells, but has no effect on mouse leukemic P388 cells in vivo, and also has a strong inhibition of Streptomyces (including the production of bacteria themselves) activity .
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Cat. No.: HY-N1649
CAS No.: 678138-59-5
2,3,2'',3''-Tetrahydroochnaflavone is a biflavonoid, which can be isolated from the leaves of Quintinia acutifolia. 2,3,2'',3''-Tetrahydroochnaflavone shows some cytotoxicity against P388 murine lymphocytic leukemia cells, with an IC50 of 8.2 µg/mL .
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Cat. No.: HY-123325
CAS No.: 132412-65-8
Kapurimycin A1 is an anbitiotic that can be isolated from Streptomyces. Kapurimycin A1 has a significant inhibitory effect on Gram-positive bacteria, exhibits cytotoxicity to cultured mammalian cells, and shows strong antitumor activity against the mouse leukemia P388 cell line .
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Cat. No.: HY-126695
CAS No.: 128461-00-7
Altromycin B is a member of the pluramycin antibiotic family isolated from South African bush soil. Altromycin B shows selective antibacterial activity against Gram-positive bacteria and has in vivo activity against P388 leukemia, colon cancer, lung cancer, and ovarian cancer.
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Cat. No.: HY-137139
CAS No.: 136803-89-9
10'-Desmethoxystreptonigrin is an inhibitor for Ras Farnesyltransferase with an IC50 of 21 μM. 10'-Desmethoxystreptonigrin is a broad-spectrum antibiotic with antibacterial activity. 10'-Desmethoxystreptonigrin exhibits antitumor activity against P388 leukemia, without significant cytotoxicity (LD50 is 8.8 mg/kg) .
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Cat. No.: HY-N10155A
CAS No.: 147138-01-0
BE-18591 shows antimicrobial activity against gram-positive and some gram-negative bacteria. BE-18591 inhibited the growth of the MKN-45 cell line (IC50= 0.285 μg/mL) and the P388 cell line (IC50= 0.52 μg/mL) .
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Cat. No.: HY-N14959
CAS No.: 114494-30-3
Deacetylravidomycin N-oxide is an antibiotic that can be produced by Streptomyces ravidus S50905. Deacetylravidomycin N-oxide is active against Gram-positive bacteria but inactive against Gram-negative bacteria. Deacetylravidomycin N-oxide has antitumor activity against P388 leukemia and methamphetamine A fibrosarcoma .
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Cat. No.: HY-N5186
CAS No.: 154277-21-1
Cypemycin is a linaridin antibiotic that can inhibit cancer cell activity, inhibits P388 leukemia cells with IC50 of 1.3 μg/mL. Cypemycin can inhibit human tumor cells such as HeLa S3, HHCC-1, HCCS-M and Slex with IC50 of >25 μg/mL .
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Cat. No.: HY-N15112
CAS No.: 138763-26-5
Target:  

Others

Pintulin can inhibit P388, L 1210, HL-60, KB and other tumor cell lines with IC50s (μg/mL) of 0.8, 0.8, 0.8, 0.25, respectively. Pintulin has only very weak antibacterial activity against the microorganisms tested .
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Cat. No.: HY-N14144
CAS No.: 182285-29-6
Cremimycin has anti-Gram-positive bacteria activity including methicillin-resistant Staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. Cremimycin shows cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro .
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Cat. No.: HY-N14020
CAS No.: 108351-52-6
Synonyms: GlbC
Glidobactin C (GlbC) is an anti-tumor antibiotic. Glidobactin C (GlbC) has the activity against pathogenic fungi and yeast. Glidobactin C has anti-Candida albicans and Aspergillus fumigatus activity with a MIC of 0.8 μg/mL. Glidobactin C also extends the survival of mice inoculated with leukemia P388 cells .
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Cat. No.: HY-N14415
CAS No.: 134769-19-0
Cochleamycin A showed strong inhibitory activity against tumor cells, with IC50s (μg/mL) of P388, HL60, K562, COL0205 and HT29 cells of 1.6, 14.0, 6.2, 16.5 and 19.1, respectively. Cochleamycin A also has anti-Gram-positive bacteria activity .
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Cat. No.: HY-N10206
CAS No.: 1319729-88-8
11-epi-Chaetomugilin I is a metabolite found in Chaetomium globosum. 11-epi-Chaetomugilin I exhibits significant cytotoxic activity against the murine P388 leukemia cell line, the human HL-60 leukemia cell line, the murine L1210 leukemia cell line, and the human KB epidermoid carcinoma cell line .
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Cat. No.: HY-117818
CAS No.: 132609-35-9
Synonyms: Antibiotic DC 116
Sapurimycin is an antitumor antibiotic isolated from Streptomyces DO-116 and belongs to the capramycin family. Sapurimycin exhibits potent activity against Gram-positive bacteria and exhibits significant antitumor effects against leukemia P388 and sarcoma 180 in mouse models. In vitro studies have shown that Sapurimycin can induce single-strand breaks in supercoiled plasmid DNA .
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Cat. No.: HY-146497
CAS No.: 2408639-81-4
Target:  

Topoisomerase

Research Areas:  

Cancer

Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones .
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Cat. No.: HY-113578
CAS No.: 101708-64-9
Target:  

Antibiotic Bacterial

Research Areas:  

Infection Cancer

PD 116152 is a phenazine Antibiotic with antimicrobial and antitumor activity. PD 116152 possesses cytotoxic activity against L1210 lymphocytic leukemia and human colon adenocarcinoma (HCT-8) cells with IC50 values of 5.2 x 10 -7 M and 7.1 x 10 -7 M, respectively. PD 116152 is promising for research of P388 lymphocytic leukemia .
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Cat. No.: HY-N18237
CAS No.: 101391-06-4
Bruceanol A is an antileukemic quassinoid glycoside isolated from Brucea javanica. Bruceanol A exhibits antileukemic activity against P-388 lymphocytic leukemia in vivo. Bruceanol A can be used in studies related to P-388 lymphocytic leukemia .
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