120 Results for "

P388

" in MedChemExpress (MCE) Product Catalog:
Products (120)

120 Results for "P388" in MCE Product Catalog:

Cat. No.: HY-126802
CAS No.: 99260-68-1
Saquayamycin B1 has antimicrobial effect, but it has weaker effect against Gram-negative bacteria. Saquayamycin B1 has inhibitory effect on leukemia P388 cells and Adriamycin-resistant P388 cells .
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Cat. No.: HY-N18086
CAS No.: 132587-61-2
Bruceanic acid D is a quassinoid compound and cytotoxic agent that can be isolated from the xylem powder of Brucea antidysenterica. Bruceanic acid D specifically inhibits P-388 lymphocytic leukemia cells but shows no activity against human lung cancer cells and human colon cancer cells. Bruceanic acid D can be used in studies related to P-388 lymphocytic leukemia .
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Cat. No.: HY-122997
CAS No.: 28937-85-1
Acetylaleuritolic acid is a triterpenoid isolated from Jatropha curcas that exhibits tumor suppressive properties against the P-388 lymphocytic leukemia test system.
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Cat. No.: HY-125321
CAS No.: 128700-84-5
Lychnostatin 2 exhibits cytotoxicity in cell P-388 with an ED50 of 0.19 µg/ml. Lychnostatin 2 can be used in research abour leukemia .
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Cat. No.: HY-N15046
CAS No.: 108147-17-7
Barminomycin I shows a strong inhibition of P388 leukemia cells with IC50 of about 0.00001 g/mL .
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Cat. No.: HY-N15047
CAS No.: 108089-33-4
Barminomycin II shows a strong inhibition of P388 leukemia cells with IC50 of about 0.00002 g/mL .
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Cat. No.: HY-117476
CAS No.: 26790-94-3
Sapelin B is a naturally occurring tirucallane-type triterpenoid that exhibits in vivo antitumor activity in a mouse model of P-388 lymphocytic leukemia. Sapelin B can be used in leukemia-related research .
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Cat. No.: HY-N9210
CAS No.: 69251-99-6
1,2,3-Tri-O-methyl-7,8-methyleneflavellagic acid, a ellagic acid derivative of Agrostistachys hookeri, exhibits activity against cultured P-388 lymphocytic leukemia cells .
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Cat. No.: HY-N8025
CAS No.: 53915-41-6
Nephthenol is a terpenoid that can be isolated from Nephthea brassica. Nephthenol exhibits cytotoxicity in cells A549, HT-29, KB and P-388 with IC50s of 2.72, 3.01, 1.84, and 0.42 µg/mL, respectively .
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Cat. No.: HY-130468
CAS No.: 160550-15-2
Leptosin J is found in the strain of Leptosphaeria sp. OUPS-4. Leptosin J inhibits Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL .
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Cat. No.: HY-182326
CAS No.: 86402-37-1
Synonyms: FR900261
Target:  

Antibiotic Fungal

Research Areas:  

Cancer

WF-3161 (FR900261) is a cyclic tetrapeptide antibiotic isolated from the fungus Petriella guttulata with anti-tumor activity. WF-3161 inhibits the growth of Trichophyton asteroides with an MIC of 3 μg/mL. WF-3161 is applicable to research related to P-388 leukemia .
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Cat. No.: HY-187763
CAS No.: 88497-93-2
Target:  

Others

Research Areas:  

Cancer

Dircin is a daphnane-type diterpene ester natural product found in the branches and flowers of Dirca occidentalis A. Gray. It exhibits potent cytotoxicity against P-388 lymphocytic leukemia cells, with a ED50 of 0.00000025 μg/mL. Dircin can be used in studies of leukemia and plant-derived cytotoxic daphnane-type diterpene esters .
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Cat. No.: HY-N21674
CAS No.: 17413-41-1
Aristolactam I N-β-D-glucoside is a naturally occurring Aristolochic acid derivative. Aristolactam I N-β-D-glucoside exhibits cytotoxicity against mouse lymphocytic leukemia P-388 cells. Aristolactam I N-β-D-glucoside can be used in leukemia-related research .
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Cat. No.: HY-N15263
CAS No.: 130743-09-8
Cepafungin III is an acylpeptide antibiotic that can be isolated from the culture broth of Pseudomonas species. Cepafungin III exhibits inhibitory activity against yeast and fungi, and antitumor activity against P388 leukemia in mice, when mixed with Cepafungin I and II .
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Cat. No.: HY-P11338
CAS No.: 297730-40-6
Target:  

Endogenous Metabolite

Research Areas:  

Cancer

Microcyclamide (Compound 1), a cytotoxic cyclic hexapeptide, is a microbial secondary metabolite. Microcyclamide can be isolated from the cyanobacterium Microcystis aeruginosa. Microcyclamide has moderate cytotoxicity against P388 murine leukemia cells with an IC50 of 1.2 μg/mL. Microcyclamide can be used for cancers research .
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Cat. No.: HY-W436478
CAS No.: 887927-59-5
Target:  

Drug Derivative

Research Areas:  

Others

(+)-2,5-epi-Goniothalesdiol is an analogue of Goniothalesdiol, which exhibits significant cytotoxicity against P388 mouse leukemia cells and has insecticidal activity. (+)-2,5-epi-Goniothalesdiol can be synthesized starting from D-mannitol (HY-N0378) .
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Cat. No.: HY-N17875
CAS No.: 124960-41-4
Synonyms: (+)-Demethylsalvicanol
Demethylsalvicanol ((+)-Demethylsalvicanol), a diterpene, is a anticancer agent with an IC50 of 0.71 μg/mL against P388 murine leukemia cells. Demethylsalvicanol induces cytotoxic activity against leukemia cells and insect Sf9 cells. Demethylsalvicanol acts as an antifeedant against Leptinotarsa decemlineata. Demethylsalvicanol can be used for the research of leukemia .
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Cat. No.: HY-N14530
CAS No.: 11050-22-9
Target:  

Bacterial

Cremeomycin has anti-Gram-positive bacteria activity including methicillin-resistant Staphylococcus aureus (MRSA), MIC is 0.2-0.39 μg/mL. Cremeomycin shows cytotoxicity to mouse tumor cell lines P388, L1210, IMC, S180, B16 and SS3 in vitro .
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Cat. No.: HY-14769B
CAS No.: 133978-76-4
Synonyms: 5,10-Methylenetetrafolate sodium; ANX-510 sodium
Target:  

Thymidylate Synthase

Research Areas:  

Cancer

Folitixorin sodium (5,10-Methylenetetrafolate sodium; ANX-510 sodium) is a reduced form of Folic acid (HY-16637) and a cofactor of thymidylate synthase . Folitixorin sodium acts as an essential cofactor to promote the formation of a tight ternary complex between thymidylate synthase and FdUMP, thereby enhancing the inhibitory effect of FdUMP on thymidylate synthase. Folitixorin sodium in combination with 5-fluorouracil and αVEGF reduces tumor volume in colorectal tumor models of nude mice. Folitixorin sodium is used in related research on Yoshida sarcoma, P-388 leukemia, and colorectal cancer .
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Cat. No.: HY-187153
CAS No.: 6003-11-8
Target:  

Topoisomerase

Research Areas:  

Metabolic Disease Cancer

Alizarin 2-methyl ether is a DNA topoisomerase inhibitor. Alizarin 2-methyl ether inhibits the relaxation of supercoiled DNA via DNA topoisomerase I and II. Alizarin 2-methyl ether promotes adipocyte differentiation by increasing lipid accumulation. Alizarin 2-methyl ether possesses antidiabetic and insulin-sensitizing properties. Alizarin 2-methyl ether can be used in research related to human colon cancer, P-388 lymphocytic leukemia and diabetes .
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