326 Results for "

serum level

" in MedChemExpress (MCE) Product Catalog:
Products (326)

326 Results for "serum level" in MCE Product Catalog:

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Cat. No.: HY-P99404
CAS No.: 2084037-83-0
Synonyms: E6011

Target:  

CXCR

Research Areas:  

Inflammation/Immunology Cancer

Quetmolimab (E6011) is a humanized anti-Fractalkine (CX3CL1) monoclonal antibody. Quetmolimab binds to membrane-bound and soluble Fractalkine, neutralizes Fractalkine-induced migration of CX3CR1-expressing cells, mediates target-bound complex elimination from serum. Quetmolimab suppresses free soluble Fractalkine levels in cynomolgus monkeys, with target engagement linked to increased serum total Fractalkine concentration. Quetmolimab can be used for the research of Crohn’s disease, rheumatoid arthritis, and primary biliary cholangitis .
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Cat. No.: HY-131926
CAS No.: 15708-41-5
Synonyms: Ethylenediaminetetraacetic acid (iron sodium)
Research Areas:  

Metabolic Disease Cancer

EDTA iron sodium (Ethylenediaminetetraacetic acid iron sodium) is an orally active food fortifier and iron chelate. EDTA iron sodium provides absorbable iron during consumption of fortified soy sauce, rice-based meals, or complementary foods made from high-phytate grains. EDTA iron sodium increases serum iron levels for up to 4 h, and total non-heme iron levels in the liver also rise with increasing doses. EDTA iron sodium is applicable to research on iron deficiency anemia and lymphoma .
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Cat. No.: HY-130675A
CAS No.: 86282-92-0
Purity:  ≥99.0%
Synonyms: 15(S)-hydroxy-Eicosapentaenoic acid; 15(S)-hydroxy EPA
Target:  

Lipoxygenase

Research Areas:  

Inflammation/Immunology

15(S)-HEPE is a monohydroxy fatty acid. 15(S)-HEPE is biosynthesized from eicosapentaenoic acid by 15-lipoxygenase (15-LO). Serum levels of 15(S)-HEPE are elevated in patients with asthma.
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Cat. No.: HY-P0056A
CAS No.: 220810-26-4
Target:  

GnRH Receptor

Research Areas:  

Cancer

Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis .
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Cat. No.: HY-108288
CAS No.: 69388-79-0
Purity:  ≥98.0%
Synonyms: Pivsulbactam; CP 47904
Research Areas:  

Infection

Sulbactam pivoxil (Pivsulbactam) is a prodrug of Sulbactam (HY-B0334) with oral activity. Sulbactam is a β-lactamase inhibitor with antibacterial activity. Sulbactam pivoxil is better absorbed than Sulbactam and results in higher serum levels after oral administration .
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Cat. No.: HY-15830
CAS No.: 29261-12-9
Purity:  95.47%
Synonyms: 25,26-Dihydroxycholecalciferol
25,26-Dihydroxyvitamin D3 (25,26-Dihydroxycholecalciferol) is a dihydroxylated derivative and metabolite of Vitamin D3 (HY-15398). 25,26-Dihydroxyvitamin D3 moderately increases serum calcium levels when the initial serum calcium level is low. 25,26-Dihydroxyvitamin D3 promotes intestinal calcium absorption in vitamin D-deficient rats fed a low-calcium diet. 25,26-Dihydroxyvitamin D3 is applicable to research related to osteomalacia .
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Cat. No.: HY-145331A
Purity:  ≥90.0%
Target:  

Arginase

Research Areas:  

Cancer

ARG1-IN-1 (Compound 3) hydrochloride is an orally active arginase inhibitor with an IC50 value of 29 nM. ARG1-IN-1 hydrochloride can inhibit serum arginase activity and increase arginine levels in mouse tumor models. ARG1-IN-1 hydrochloride is applicable for tumor research .
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Cat. No.: HY-100485
CAS No.: 149556-49-0
Target:  

Drug Derivative

Research Areas:  

Inflammation/Immunology

Susalimod is an immunomodulating agent and Sulfasalazine (HY-14655) analogue. Susalimod decreases LPS-induced TNF-alpha mouse serum levels .
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Cat. No.: HY-N0136B
CAS No.: 111003-33-9
Synonyms: (-)-Dihydroquercetin
(-)-Taxifolin is the low-activity isomer of Taxifolin. Taxifolin is an orally effective collagenase inhibitor with an IC50 of 193.3 μM. Taxifolin dose-dependently reduces the levels of Smad-2, α-SMA, CTGF, type I collagen, NF-κB and FN in renal tissues, while decreasing serum levels of IL-1β, TNF-α, MDA, Scr and BUN, increasing SOD levels and reversing 27 serum metabolic biomarkers. Taxifolin inhibits the growth of a variety of pathogenic bacteria. Taxifolin can be used in studies related to renal fibrosis .
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Cat. No.: HY-P0056
CAS No.: 76712-82-8
Target:  

GnRH Receptor

Research Areas:  

Cancer

Histrelin, a GnRH analogue, is a GnRH Receptor agonist. Histrelin increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin can be used in the research of prostate cancer, endometriosis .
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Cat. No.: HY-146273
CAS No.: 2411698-59-2
Target:  

Xanthine Oxidase

Research Areas:  

Metabolic Disease

Xanthine oxidase-IN-7 (compound1h) is a potent andorally active XO (xanthine oxidase) inhibitor with an IC50 of 0.36 µM. Xanthine oxidase-IN-7 effectively reduces serum uric acid levels. Xanthine oxidase-IN-7 has the potential for the research of hyperuricemia and gout .
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Cat. No.: HY-126995R
CAS No.: 13042-33-6
Glycohyodeoxycholic acid (Standard) is the analytical standard of Glycohyodeoxycholic acid. This product is intended for research and analytical applications. Glycohyodeoxycholic acid is a glycine-conjugated bile acid and also a metabolite of Hyodeoxycholic acid (HY-N0169). The serum level of Glycohyodeoxycholic acid is negatively correlated with the severity of non-alcoholic fatty liver disease. Glycohyodeoxycholic acid can be used in research related to non-alcoholic fatty liver disease.
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Cat. No.: HY-P4838
CAS No.: 154765-04-5
Target:  

Inhibitory Antibodies

Research Areas:  

Others

pTH (2-38) (human) is involved in the anabolic action of bone. PTH (2-38) can increase the level of serum INS-PTH (complete N-terminal specific PTH) .
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Cat. No.: HY-W012946S
CAS No.: 40073-83-4
2-Furoic acid-d3 is the deuterium labeled 2-Furoic acid . 2-Furoic acid (Furan-2-carboxylic acid) is an organic compound produced through furfural oxidation . 2-Furoic acid exhibits hypolipidemic effet, lowers both serum cholesterol and serum triglyceride levels in rats .
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Cat. No.: HY-P4835
CAS No.: 247902-18-7
Target:  

Phosphatase

Research Areas:  

Others

pTH (2-34) (human) (80 μg/kg) slightly increases serum osteocalcin levels and alkaline phosphatase activity of bone extract (markers of bone formation) in mice. pTH (2-34) is not as effective as pTH (1-34) .
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Cat. No.: HY-13995
CAS No.: 52757-95-6
Target:  

FXR

Research Areas:  

Metabolic Disease Endocrinology

Sevelamer is an orally active polymeric phosphate binder and bile acid sequestrant. Sevelamer binds dietary phosphate in the gastrointestinal tract, reducing phosphate absorption and serum phosphorus levels, and reduces urinary phosphate excretion. Sevelamer binds polyanion bile acids, increases bile acid faecal excretion, and reduces total cholesterol and LDL cholesterol levels. Sevelamer can be used for the research of hyperphosphataemia, hyperparathyroidism, chronic renal failure, kidney disease, and type 2 diabetes .
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Cat. No.: HY-145331
CAS No.: 2376189-62-5
Target:  

Arginase

Research Areas:  

Cancer

ARG1-IN-1 (Compound 3) is an orally active arginase inhibitor with an IC50 value of 29 nM. ARG1-IN-1 can inhibit serum arginase activity and increase arginine levels in mouse tumor models. ARG1-IN-1 is applicable for tumor research .
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Cat. No.: HY-19852
CAS No.: 876145-69-6
Target:  

PPAR

Research Areas:  

Metabolic Disease

KRP-105 is a potent, highly selective, and orally effective PPAR alpha (EC50 = 8 nM) agonist. KRP-105 can significantly reduce serum triglyceride, total cholesterol, and non high density lipoprotein cholesterol levels. KRP-105 can be used for research on metabolic diseases such as dyslipidemia .
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Cat. No.: HY-W011824S
2′-O-Methyluridine-d3 is deuterium labeled 2′-O-Methyluridine (HY-W011824).2’-O-Methyluridine is a modified nucleoside that can be found in T. thermophile tRNA. 2’-O-Methyluridine level in serum is decreased in patients with breast cancer .
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Cat. No.: HY-W047156
CAS No.: 69391-08-8
Research Areas:  

Endocrinology

Allantoxanamide is a uricase inhibitor that induces hyperuricemia by inhibiting uric acid degradation. Allantoxanamide inhibits uricase activity in vitro with an IC50 of approximately 0.9 μM and increases serum uric acid levels in rats. Allantoxanamide can be used for the study of hyperuricemia, uric acid metabolism, hyperuricemia-associated nephropathy, and related metabolic research .
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