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Cat. No.: HY-108288

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Sulbactam pivoxil

Name: Sulbactam pivoxil
Brand: MedChemExpress
SKU: HY-108288
Price: 70.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: Pivsulbactam; CP 47904)

Customer Review

Based on 1 Customer Validation

Sulbactam pivoxil (Pivsulbactam) is a prodrug of Sulbactam (HY-B0334) with oral activity. Sulbactam is a β-lactamase inhibitor with antibacterial activity. Sulbactam pivoxil is better absorbed than Sulbactam and results in higher serum levels after oral administration.

For research use only. We do not sell to patients.

Purity: 98.0%
CAS No.: 69388-79-0
Formula: C₁₄H₂₁NO₇S
Molecular Weight:347.38

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Sulbactam pivoxil Chemical Structure

CAS No.: 69388-79-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Beta-lactamase Isoforms :

All Antibiotic Isoforms :

In Vivo

Pharmacokinetic Analysis in Fasted Rats^[2]

Route	Dose, mg/kg	t_1/2, h	C_max, sulbactam equivalents, μg/mL	AUC, μg·mL h	ratio
p.o.	10	1.5	6.2	8.5	1.0

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 69388-79-0
Appearance Solid
Molecular Weight 347.38
Formula C₁₄H₂₁NO₇S
Color White to off-white
SMILES

O=C([C@@H](C(C)(C)S([C@]1([H])C2)(=O)=O)N1C2=O)OCOC(C(C)(C)C)=O
Synonyms

Pivsulbactam; CP 47904
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 12.5 mg/mL (35.98 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.8787 mL

14.3935 mL

28.7869 mL

5 mM

0.5757 mL

2.8787 mL

5.7574 mL

10 mM

0.2879 mL

1.4393 mL

2.8787 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight Molecular Weight

Dilution Calculator

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Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (284 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Changov LS, et al. An efficient method for the synthesis of sulbactam pivoxil. Farmaco. 2000;55(2):134-135. [Content Brief]

[2]. English A R, et al. Orally effective acid prodrugs of the. beta.-lactamase inhibitor sulbactam. Journal of medicinal chemistry, 1990, 33(1): 344-347. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.8787 mL	14.3935 mL	28.7869 mL	71.9673 mL
	5 mM	0.5757 mL	2.8787 mL	5.7574 mL	14.3935 mL
	10 mM	0.2879 mL	1.4393 mL	2.8787 mL	7.1967 mL
	15 mM	0.1919 mL	0.9596 mL	1.9191 mL	4.7978 mL
	20 mM	0.1439 mL	0.7197 mL	1.4393 mL	3.5984 mL
	25 mM	0.1151 mL	0.5757 mL	1.1515 mL	2.8787 mL
	30 mM	0.0960 mL	0.4798 mL	0.9596 mL	2.3989 mL

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

Sulbactam pivoxil

All Beta-lactamase Isoforms

All Antibiotic Isoforms

Biological Activity

Description

In Vivo

Chemical Information

Solvent & Solubility

In Vitro:

Purity & Documentation

References

Help & FAQs

Complete Stock Solution Preparation Table

Sulbactam pivoxil Related Classifications

HY-108288 Related Classifications

Bioz

Keywords

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