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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
199 Results for "
ALDH
" in MedChemExpress (MCE) Product Catalog:
Products (199)
199 Results for "ALDH" in MCE Product Catalog:
Cat. No.: HY-W207195
CAS No.: 2555-30-8
Synonyms: 4-Phenylumbelliferone
Research Areas:
7-Hydroxy-4-phenylcoumarin is a dual ALDH-2 and MAO inhibitor, with IC50 values of 1.5 and 0.5 µM, respectively .
Cat. No.: HY-D3183
CAS No.: 1623011-10-8
Cat. No.: HY-W016645R
CAS No.: 120-21-8
Research Areas:
4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM) .
Cat. No.: HY-D3182
CAS No.: 2252329-12-5
Synonyms: Daidzoside (Standard); NPI-031D (Standard); Daidzein 7-O-glucoside (Standard)
Synonyms: N42
Target:
Research Areas:
FSI-TN42 (N42) is a selective, orally active and irreversible ALDH1A1 inhibitor with an IC50 of 23 nM. FSI-TN42 shows 800-fold more potent against ALDH1A1 than ALDH1A2 (IC50
Cat. No.: HY-177639A
CAS No.: 2728713-54-8
Synonyms: NN-6020 sodium
Target:
Research Areas:
Lefelsiran sodium is a siRNA targeted to ALDH2. It is used for the study of alcohol use disorder.
Cat. No.: HY-D3185
CAS No.: 2243148-62-9
Cat. No.: HY-135214
CAS No.: 851053-64-0
Target:
Research Areas:
GA11 is an ALDH inhibitor that shows activity against glioblastoma both in vitro and in vivo .
Research Areas:
Sulfiram is a very weak aldehyde dehydrogenase (ALDH) inhibitor, with an IC50 value of 413 μM against Saccharomyces cerevisiae ALDH. As a photochemical precursor, Sulfiram undergoes photoconversion to form Disulfiram (HY-B0240), a potent ALDH inhibitor. Sulfiram inhibits the dimerization of the extracellular domain fragment (amino acid residues 230-624) of amyloid precursor protein (APP), alters the monomer-dimer equilibrium, induces conformational changes in the fragment, and enhances the production of sAPPα via α-cleavage of APP. Sulfiram can be used in research related to scabies and Alzheimer's disease .
Cat. No.: HY-177639
CAS No.: 2765645-87-0
Synonyms: NN-6020
Target:
Research Areas:
Lefelsiran (NN-6020) is a siRNA targeted to ALDH2. It is used for the study of alcohol use disorder.
Cat. No.: HY-18768A
CAS No.: 2080306-22-3
Target:
Research Areas:
NCT-501 hydrochloride is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC50 >57 μM) .
Target:
Research Areas:
NCT-506 is an orally bioavailable aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitors with an IC50 of 7 nM .
Cat. No.: HY-129314
CAS No.: 361156-54-9
Target:
Research Areas:
CM-39 is a non-covalent and reversible inhibitor for aldehyde dehydrogenase 1A (ALDH1A) with an IC50 of 0.9 μM .
Cat. No.: HY-168985
CAS No.: 1804941-96-5
Target:
Research Areas:
Mirivadelgat is an activator of aldehyde dehydrogenase 2 (ALDH2). Mirivadelgat is used for research on interstitial lung disease-associated pulmonary hypertension and cancer .
Target:
Research Areas:
EN40 is a potent, selective aldehyde dehydrogenase 3A1 (ALDH3A1) inhibitor as a covalent ligand, exhibits an IC50 value of 2 uM
Cat. No.: HY-124766
CAS No.: 350229-29-7
Target:
Research Areas:
ABD-3001 is an inhibitor of ALDH1. ABD-3001 can be studied in research on refractory/relapsed acute myeloid leukemia and high-risk myelodysplastic syndrome .
Cat. No.: HY-139005
CAS No.: 247069-93-8
Synonyms: BAAA-DA
Target:
Research Areas:
BODIPY aminoacetaldehyde diethyl acetal is a stable precursor to BODIPY-aminoacetaldehyde and can be converted into BODIPY-aminoacetaldehyde under acidic conditions. BODIPY-aminoacetaldehyde is a fluorescent substrate for aldehyde dehydrogenase (ALDH) .
Cat. No.: HY-139032
CAS No.: 2204230-40-8
Target:
Research Areas:
CM121 is an active site-directed reversible ALDH1A2 inhibitor (IC50=0.54 μM；Kd=1.1 μM) with a variety of hydrophobic interactions .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
